Literature DB >> 28473036

Ethical Analysis of Withdrawing Total Artificial Heart Support.

Erin S DeMartino1, Sara E Wordingham2, John M Stulak3, Barry A Boilson4, Kayla R Fuechtmann5, Nausheen Singh6, Daniel P Sulmasy7, Octavio E Pajaro8, Paul S Mueller9.   

Abstract

OBJECTIVES: To describe the characteristics of patients who undergo withdrawal of total artificial heart support and to explore the ethical aspects of withdrawing this life-sustaining treatment. PATIENTS AND METHODS: We retrospectively reviewed the medical records of all adult recipients of a total artificial heart at Mayo Clinic from the program's inception in 2007 through June 30, 2015. Management of other life-sustaining therapies, approach to end-of-life decision making, engagement of ethics and palliative care consultation, and causes of death were analyzed.
RESULTS: Of 47 total artificial heart recipients, 14 patients or their surrogates (30%) requested withdrawal of total artificial heart support. No request was denied by treatment teams. All 14 patients were supported with at least 1 other life-sustaining therapy. Only 1 patient was able to participate in decision making.
CONCLUSION: It is widely held to be ethically permissible to withdraw a life-sustaining treatment when the treatment no longer meets the patient's health care-related goals (ie, the burdens outweigh the benefits). These data suggest that some patients, surrogates, physicians, and other care providers believe that this principle extends to the withdrawal of total artificial heart support.
Copyright © 2017 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28473036      PMCID: PMC5653372          DOI: 10.1016/j.mayocp.2017.01.021

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  22 in total

1.  Legal rights to health care at the end of life.

Authors:  L P Francis
Journal:  JAMA       Date:  1999-12-01       Impact factor: 56.272

2.  Cruzan v. Director, Missouri Department of Health.

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3.  American College of Physicians Ethics Manual: sixth edition.

Authors:  Lois Snyder
Journal:  Ann Intern Med       Date:  2012-01-03       Impact factor: 25.391

4.  Results with SynCardia total artificial heart beyond 1 year.

Authors:  Gianluca Torregrossa; Michiel Morshuis; Robin Varghese; Leila Hosseinian; Vladimiro Vida; Vincenzo Tarzia; Antonio Loforte; Daniel Duveau; Francisco Arabia; Pascal Leprince; Vigneshwa Kasirajan; Friedhelm Beyersdorf; Francesco Musumeci; Roland Hetzer; Thoamas Krabatsch; Jan Gummert; Jack Copeland; Gino Gerosa
Journal:  ASAIO J       Date:  2014 Nov-Dec       Impact factor: 2.872

Review 5.  Total artificial hearts: past, present, and future.

Authors:  William E Cohn; Daniel L Timms; O H Frazier
Journal:  Nat Rev Cardiol       Date:  2015-06-02       Impact factor: 32.419

6.  Ethical analysis of withdrawing ventricular assist device support.

Authors:  Paul S Mueller; Keith M Swetz; Monica R Freeman; Kari A Carter; Mary Eliot Crowley; Cathy J Anderson Severson; Soon J Park; Daniel P Sulmasy
Journal:  Mayo Clin Proc       Date:  2010-06-28       Impact factor: 7.616

7.  Present and future perspectives on total artificial hearts.

Authors:  Gino Gerosa; Silvia Scuri; Laura Iop; Gianluca Torregrossa
Journal:  Ann Cardiothorac Surg       Date:  2014-11

8.  Destination nowhere: a potential dilemma with ventricular assist devices.

Authors:  Katrina A Bramstedt
Journal:  ASAIO J       Date:  2008 Jan-Feb       Impact factor: 2.872

9.  Cardiac replacement with a total artificial heart as a bridge to transplantation.

Authors:  Jack G Copeland; Richard G Smith; Francisco A Arabia; Paul E Nolan; Gulshan K Sethi; Pei H Tsau; Douglas McClellan; Marvin J Slepian
Journal:  N Engl J Med       Date:  2004-08-26       Impact factor: 91.245

10.  Killing and allowing to die: another look.

Authors:  D P Sulmasy
Journal:  J Law Med Ethics       Date:  1998       Impact factor: 1.718

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  1 in total

Review 1.  Ethical and Legal Concerns Associated With Withdrawing Mechanical Circulatory Support: A U.S. Perspective.

Authors:  Paul S Mueller
Journal:  Front Cardiovasc Med       Date:  2022-07-26
  1 in total

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