Literature DB >> 28472515

Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity.

Thazha P Prakash1, Walt F Lima1, Heather M Murray1, Wenyu Li1, Garth A Kinberger1, Alfred E Chappell1, Hans Gaus1, Punit P Seth1, Balkrishen Bhat1, Stanley T Crooke1, Eric E Swayze1.   

Abstract

Entities:  

Year:  2017        PMID： 28472515      PMCID： PMC5499767          DOI： 10.1093/nar/gkx381

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


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Nucleic Acids Res (2015) 43 (6): 2993–3011. doi:10.1093/nar/gkv162 The Authors wish to apologise for an error in Figure 14 of the above article where they have used T instead of U in the sequences. The T at the 5΄-end of the sequence are correct. A new figure is provided below. This correction does not affect the results and conclusion of the article. These errors have also been corrected in the original article.
Figure 14.

In vitro activity of (E)-5΄-VP modified ss-siRNA targeting ApoC III mRNA.

In vitro activity of (E)-5΄-VP modified ss-siRNA targeting ApoC III mRNA.
  3 in total

Review 1.  RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials.

Authors:  Eunice L Lozada-Delgado; Nilmary Grafals-Ruiz; Pablo E Vivas-Mejía
Journal:  Life Sci       Date:  2017-08-31       Impact factor: 5.037

2.  Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.

Authors:  Matthew R Hassler; Anton A Turanov; Julia F Alterman; Reka A Haraszti; Andrew H Coles; Maire F Osborn; Dimas Echeverria; Mehran Nikan; William E Salomon; Loïc Roux; Bruno M D C Godinho; Sarah M Davis; David V Morrissey; Phillip D Zamore; S Ananth Karumanchi; Melissa J Moore; Neil Aronin; Anastasia Khvorova
Journal:  Nucleic Acids Res       Date:  2018-03-16       Impact factor: 16.971

3.  Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1.

Authors:  Sarah M Davis; Vignesh N Hariharan; Agnes Lo; Anton A Turanov; Dimas Echeverria; Jacquelyn Sousa; Nicholas McHugh; Annabelle Biscans; Julia F Alterman; S Ananth Karumanchi; Melissa J Moore; Anastasia Khvorova
Journal:  Mol Ther Nucleic Acids       Date:  2022-06-22       Impact factor: 10.183
  3 in total

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