Lai-Yan Wong1,2, Siew-Siang Chua1, Abdul-Rahman Husin3, Hanisah Arshad4. 1. Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. 2. Unit of Pharmacy, Maharani Health Clinic, Muar, Malaysia. 3. Outpatient Department, Maharani Health Clinic, Muar, Malaysia. 4. Outpatient Department, Bakri Health Clinic, Muar, Malaysia.
Abstract
Background: Although clinical guidelines are available for the management of asthma, this health condition is still poorly managed in many countries. Objectives: To assess the effects of a Pharmacy Management Service (PharMS) on asthma control of adult patients. Methods: This study comprised of a cluster randomised controlled trial (RCT) that was conducted from April 2014 to July 2015 at four government health clinics. The control participants received usual pharmacy service, while the intervention participants were recruited into the PharMS. Each participant was monitored for 6 months, and the outcome measures included asthma control using the Asthma Control Test (ACT), inhaler technique using a checklist and medication adherence using the Malaysian Medication Adherence Scale. Results:A total of 157 participants were recruited: 77 in the control and 80 in the intervention group. At the end of the study, 90% of the intervention participants achieved well-controlled asthma compared to 28.6% in the control group (P < 0.001). The differences in the proportion of participants with correct inhaler technique was also significant, with an adjusted effect size of 0.953 (P < 0.001). In addition, the intervention participants showed significantly higher medication adherence than the control group (92.5% versus 45.5%, P < 0.001). The Generalised Estimated Equation analysis further confirmed that the PharMS (P < 0.001) was significantly related to an improvement in the ACT scores. Conclusion: A community-based asthma management program, the PharMS, that provided asthma education and skill training by a trained pharmacist, resulted in positive and significant improvements in clinical and management outcomes of adult asthma patients.
RCT Entities:
Background: Although clinical guidelines are available for the management of asthma, this health condition is still poorly managed in many countries. Objectives: To assess the effects of a Pharmacy Management Service (PharMS) on asthma control of adult patients. Methods: This study comprised of a cluster randomised controlled trial (RCT) that was conducted from April 2014 to July 2015 at four government health clinics. The control participants received usual pharmacy service, while the intervention participants were recruited into the PharMS. Each participant was monitored for 6 months, and the outcome measures included asthma control using the Asthma Control Test (ACT), inhaler technique using a checklist and medication adherence using the Malaysian Medication Adherence Scale. Results: A total of 157 participants were recruited: 77 in the control and 80 in the intervention group. At the end of the study, 90% of the intervention participants achieved well-controlled asthma compared to 28.6% in the control group (P < 0.001). The differences in the proportion of participants with correct inhaler technique was also significant, with an adjusted effect size of 0.953 (P < 0.001). In addition, the intervention participants showed significantly higher medication adherence than the control group (92.5% versus 45.5%, P < 0.001). The Generalised Estimated Equation analysis further confirmed that the PharMS (P < 0.001) was significantly related to an improvement in the ACT scores. Conclusion: A community-based asthma management program, the PharMS, that provided asthma education and skill training by a trained pharmacist, resulted in positive and significant improvements in clinical and management outcomes of adult asthmapatients.
Authors: Konrad Schultz; Michael Wittmann; Rupert Wagner; Nicola Lehbert; Larissa Schwarzkopf; Boglárka Szentes; Dennis Nowak; Hermann Faller; Michael Schuler Journal: Dtsch Arztebl Int Date: 2021-01-22 Impact factor: 5.594
Authors: Ai Theng Cheong; Ping Yein Lee; Sazlina Shariff-Ghazali; Hani Salim; Norita Hussein; Rizawati Ramli; Hilary Pinnock; Su May Liew; Nik Sherina Hanafi; Ahmad Ihsan Abu Bakar; Azainorsuzila Mohd Ahad; Yong Kek Pang; Karuthan Chinna; Ee Ming Khoo Journal: NPJ Prim Care Respir Med Date: 2021-11-29 Impact factor: 2.871