Reza Forghani1, Hillary Kelly, Eugene Yu, Manon Belair, Laurent Létourneau-Guillon, Huy Le, Francesca Proulx, Thomas Ong, Xianming Tan, Hugh D Curtin, Mark Levental. 1. From the *Department of Radiology, †Segal Cancer Centre, ‡Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; §Department of Radiology, Massachusetts General Hospital, ∥Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA; ¶Joint Department of Medical Imaging, Princess Margaret Hospital, University Health Network, University of Toronto, Toronto, Ontario; #Department of Radiology, Hôpital Notre-Dame du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada; and **Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC.
Abstract
OBJECTIVE: Dual-energy computed tomography (CT) 40-keV virtual monochromatic images (VMIs) have been reported to improve visualization of head and neck squamous cell carcinoma, but a direct comparison to single-energy CT (SECT) is lacking, and there is debate regarding subjective user preference. We compared 40-keV VMIs with SECT and performed a subjective evaluation of their utility and acceptability for clinical use. METHODS: A total of 60 dual-energy CT and 60 SECT scans from 2 different institutions were evaluated. Tumor conspicuity was evaluated objectively using absolute and relative attenuation and subjectively by 3 head and neck specialists and 3 general radiologists. RESULTS: Tumors had significantly higher absolute and relative attenuation on 40-keV VMIs (P < 0.0001). Subjectively, the 40-keV VMIs improved visualization, with substantial (κ, 0.61-0.80) to almost perfect (κ, 0.81-1) interrater agreements. CONCLUSIONS: The 40-keV VMIs improve tumor visibility objectively and subjectively both by head and neck specialists and general radiologists.
OBJECTIVE: Dual-energy computed tomography (CT) 40-keV virtual monochromatic images (VMIs) have been reported to improve visualization of head and neck squamous cell carcinoma, but a direct comparison to single-energy CT (SECT) is lacking, and there is debate regarding subjective user preference. We compared 40-keV VMIs with SECT and performed a subjective evaluation of their utility and acceptability for clinical use. METHODS: A total of 60 dual-energy CT and 60 SECT scans from 2 different institutions were evaluated. Tumor conspicuity was evaluated objectively using absolute and relative attenuation and subjectively by 3 head and neck specialists and 3 general radiologists. RESULTS: Tumors had significantly higher absolute and relative attenuation on 40-keV VMIs (P < 0.0001). Subjectively, the 40-keV VMIs improved visualization, with substantial (κ, 0.61-0.80) to almost perfect (κ, 0.81-1) interrater agreements. CONCLUSIONS: The 40-keV VMIs improve tumor visibility objectively and subjectively both by head and neck specialists and general radiologists.
Authors: Fabian K Lohöfer; Georgios A Kaissis; Frances L Köster; Sebastian Ziegelmayer; Ingo Einspieler; Carlos Gerngross; Michael Rasper; Peter B Noel; Steffen Koerdt; Andreas Fichter; Ernst J Rummeny; Rickmer F Braren Journal: Eur Radiol Date: 2018-05-28 Impact factor: 5.315
Authors: Andra-Iza Iuga; Jonas Doerner; Florian Siedek; Stefan Haneder; Jonathan Byrtus; Julian A Luetkens; David Maintz; Tilman Hickethier Journal: Medicine (Baltimore) Date: 2019-08 Impact factor: 1.817