Literature DB >> 28471478

Probiotics for the prevention of necrotising enterocolitis in very low-birth-weight infants: a meta-analysis and systematic review.

John P Thomas1, Tim Raine2, Sanath Reddy3, Gusztav Belteki4.   

Abstract

We performed an updated meta-analysis incorporating the results of recent randomised controlled trials (RCTs) to measure the effectiveness of probiotic supplementation in preventing necrotising enterocolitis (NEC) and death in very low-birth-weight (VLBW) infants, and to investigate any differences in efficacy by probiotic agent. Using meta-regression analysis, we assessed the contribution of other measured variables on the overall effect size and between-study variability.
CONCLUSION: Overall, probiotics lead to significant reductions in NEC incidence and mortality in VLBW infants. Differences in probiotic agents and the influence of prenatal steroids and feeding regimens may explain the differences in outcomes between studies. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Necrotising enterocolitis; Nutrition; Probiotics; Very low-birth-weight infant

Mesh:

Year:  2017        PMID: 28471478     DOI: 10.1111/apa.13902

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  21 in total

Review 1.  Probiotics and necrotizing enterocolitis.

Authors:  Ravi Mangal Patel; Mark A Underwood
Journal:  Semin Pediatr Surg       Date:  2017-11-06       Impact factor: 2.754

Review 2.  To start or not: Factors to consider when implementing routine probiotic use in the NICU.

Authors:  Maria E Barbian; Rachel Buckle; Patricia Wei Denning; Ravi Mangal Patel
Journal:  Early Hum Dev       Date:  2019-06-10       Impact factor: 2.079

Review 3.  New insights into necrotizing enterocolitis: From laboratory observation to personalized prevention and treatment.

Authors:  David J Hackam; Chhinder P Sodhi; Misty Good
Journal:  J Pediatr Surg       Date:  2018-06-18       Impact factor: 2.545

Review 4.  Probiotic sepsis in preterm neonates-a systematic review.

Authors:  Tithi Kulkarni; Swati Majarikar; Mangesh Deshmukh; Anitha Ananthan; Haribalakrishna Balasubramanian; Anthony Keil; Sanjay Patole
Journal:  Eur J Pediatr       Date:  2022-03-29       Impact factor: 3.183

Review 5.  Manipulating the neonatal gut microbiome: current understanding and future perspectives.

Authors:  Emma Wong; Kei Lui; Andrew S Day; Steven T Leach
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2021-08-25       Impact factor: 6.643

Review 6.  Next-Generation Probiotic Therapy to Protect the Intestines From Injury.

Authors:  Mecklin V Ragan; Samantha J Wala; Steven D Goodman; Michael T Bailey; Gail E Besner
Journal:  Front Cell Infect Microbiol       Date:  2022-06-28       Impact factor: 6.073

7.  Prophylactic Probiotic Supplementation for Preterm Neonates-A Systematic Review and Meta-Analysis of Nonrandomized Studies.

Authors:  Mangesh Deshmukh; Sanjay Patole
Journal:  Adv Nutr       Date:  2021-07-30       Impact factor: 8.701

8.  Lactobacillus reuteri Colonisation of Extremely Preterm Infants in a Randomised Placebo-Controlled Trial.

Authors:  Johanne E Spreckels; Erik Wejryd; Giovanna Marchini; Baldvin Jonsson; Dylan H de Vries; Maria C Jenmalm; Eva Landberg; Eva Sverremark-Ekström; Magalí Martí; Thomas Abrahamsson
Journal:  Microorganisms       Date:  2021-04-24

9.  Clinical implications of preterm infant gut microbiome development.

Authors:  David B Healy; C Anthony Ryan; R Paul Ross; Catherine Stanton; Eugene M Dempsey
Journal:  Nat Microbiol       Date:  2021-12-23       Impact factor: 17.745

10.  Probiotic supplementation in preterm infants does not affect the risk of retinopathy of prematurity: a meta-analysis of randomized controlled trials.

Authors:  Giacomo Cavallaro; Eduardo Villamor-Martínez; Luca Filippi; Fabio Mosca; Eduardo Villamor
Journal:  Sci Rep       Date:  2017-10-12       Impact factor: 4.379

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