Literature DB >> 2846886

The putative trans-activator in the MAgag region of Rous sarcoma virus is not required for cell transformation.

A Dutta1, T Dorai, H Hanafusa.   

Abstract

A stop codon created by oligonucleotide-directed mutagenesis in the proposed transcriptional trans-activator of Rous sarcoma virus (S. Broome and W. Gilbert, Cell 40:537-546, 1985) which truncated the trans-activator by half did not alter the transforming activity or the replication of the virus in primary chicken embryo fibroblasts. This result proves that this trans-activator is not essential for transformation of primary cells by Rous sarcoma virus.

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Year:  1988        PMID: 2846886      PMCID: PMC253595     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  17 in total

1.  cis-acting regulatory elements within gag genes of avian retroviruses.

Authors:  S Arrigo; M Yun; K Beemon
Journal:  Mol Cell Biol       Date:  1987-01       Impact factor: 4.272

2.  Standardized and simplified nomenclature for proteins common to all retroviruses.

Authors:  J Leis; D Baltimore; J M Bishop; J Coffin; E Fleissner; S P Goff; S Oroszlan; H Robinson; A M Skalka; H M Temin
Journal:  J Virol       Date:  1988-05       Impact factor: 5.103

3.  Specific nuclear proteins interact with the Rous sarcoma virus internal enhancer and share a common element with the enhancer located in the long terminal repeat of the virus.

Authors:  L Karnitz; S Faber; R Chalkley
Journal:  Nucleic Acids Res       Date:  1987-12-10       Impact factor: 16.971

4.  Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product.

Authors:  P Whyte; K J Buchkovich; J M Horowitz; S H Friend; M Raybuck; R A Weinberg; E Harlow
Journal:  Nature       Date:  1988-07-14       Impact factor: 49.962

5.  Nucleotide sequence of Rous sarcoma virus.

Authors:  D E Schwartz; R Tizard; W Gilbert
Journal:  Cell       Date:  1983-03       Impact factor: 41.582

6.  Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus.

Authors:  R Swanstrom; H E Varmus; J M Bishop
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

7.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors:  H Land; L F Parada; R A Weinberg
Journal:  Nature       Date:  1983 Aug 18-24       Impact factor: 49.962

8.  Molecular cloning and characterization of avian sarcoma virus circular DNA molecules.

Authors:  W J DeLorbe; P A Luciw; H M Goodman; H E Varmus; J M Bishop
Journal:  J Virol       Date:  1980-10       Impact factor: 5.103

Review 9.  Fos-associated protein p39 is the product of the jun proto-oncogene.

Authors:  F J Rauscher; D R Cohen; T Curran; T J Bos; P K Vogt; D Bohmann; R Tjian; B R Franza
Journal:  Science       Date:  1988-05-20       Impact factor: 47.728

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

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  1 in total

1.  Role of gag sequence in the biochemical properties and transforming activity of the avian sarcoma virus UR2-encoded gag-ros fusion protein.

Authors:  S M Jong; L H Wang
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

  1 in total

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