| Literature DB >> 2846886 |
A Dutta1, T Dorai, H Hanafusa.
Abstract
A stop codon created by oligonucleotide-directed mutagenesis in the proposed transcriptional trans-activator of Rous sarcoma virus (S. Broome and W. Gilbert, Cell 40:537-546, 1985) which truncated the trans-activator by half did not alter the transforming activity or the replication of the virus in primary chicken embryo fibroblasts. This result proves that this trans-activator is not essential for transformation of primary cells by Rous sarcoma virus.Entities:
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Year: 1988 PMID: 2846886 PMCID: PMC253595
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103