Literature DB >> 28467915

Revealing the Inter-Module Interactions of Multi-Modular Nonribosomal Peptide Synthetases.

J Shaun Lott1, T Verne Lee2.   

Abstract

Nonribosomal peptide synthetase (NRPS) enzymes are large modular proteins involved in the biosynthesis of many important pharmaceuticals such as penicillin and cyclosporin. In this issue of Structure, Tarry et al. (2017) use X-ray crystallography and electron microscopy to shed light on the inter-module interactions that underpin the complex function of these enzymes.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28467915     DOI: 10.1016/j.str.2017.04.003

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  2 in total

1.  Inter-Modular Linkers play a crucial role in governing the biosynthesis of non-ribosomal peptides.

Authors:  Sherif Farag; Rachel M Bleich; Elizabeth A Shank; Olexandr Isayev; Albert A Bowers; Alexander Tropsha
Journal:  Bioinformatics       Date:  2019-10-01       Impact factor: 6.937

2.  Pyoverdine-Mediated Killing of Caenorhabditis elegans by Pseudomonas syringae MB03 and the Role of Iron in Its Pathogenicity.

Authors:  Anum Bashir; Tian Tian; Xun Yu; Cui Meng; Muhammad Ali; Lin Li
Journal:  Int J Mol Sci       Date:  2020-03-22       Impact factor: 5.923

  2 in total

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