| Literature DB >> 28466570 |
Terry Boyle1,2, Joseph M Connors3, Randy D Gascoyne3, Brian R Berry4, Laurie H Sehn3, Morteza Bashash5, John J Spinelli6,7.
Abstract
There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0·59, 95% confidence interval (CI) = 0·36-0·96], while obese follicular lymphoma cases had a 2·5-fold risk of dying (HR = 2·52, 95% CI = 1·27-5·00) compared with cases with normal BMI. NHL-specific survival results were similar.Entities:
Keywords: body mass index; diffuse large B-cell lymphoma; follicular lymphoma; physical activity; prognosis
Mesh:
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Year: 2017 PMID: 28466570 DOI: 10.1111/bjh.14702
Source DB: PubMed Journal: Br J Haematol ISSN: 0007-1048 Impact factor: 6.998