Literature DB >> 28466404

Vascular Anomalies: A Pediatric Surgeon's Perspective.

Alisha Gupta1, Ajay Verma1, Anjan Dhua1, Veereshwar Bhatnagar2.   

Abstract

Anomalies affecting the capillary and venous channels form the bulk of the spectrum of vascular anomalies. As per International Society for the Study of Vascular Anomalies (ISSVA) classification, these are referred to as hemangiomas and venous malformations respectively. The present article is a descriptive note of their management and outcomes. Retrospective records of patients over 17 y (January 2000 through December 2016) were reviewed for presentation, management and outcomes. Outcomes were graded into 3 subgroups based on subjective assessment of clinical images: Group A = near-total response (>90%); Group B = 50-90% and Group C = <50% reduction. Among 90 cases of hemangioma, majority were located in head and neck (86.7%). Outcomes recorded in children who received steroids (n = 36) were: Group A = 61.1%, B = 25% and C = 13.9%; steroids and beta-blockers (n = 8): Group A = 62.5%, B = 25% and C = 12.5%; only beta-blockers (n = 4): Group A = 75% and B = 25%; intralesional sclerotherapy (n = 32): Group A = 55.2% and B = 44.8%; steroids followed by sclerotherapy (n = 7): Group A = 28.6% and B = 71.4%; excision (n = 3): Group A = 100%. Among 171 cases of venous malformation, majority were located in head and neck (49.6%). Outcomes recorded in children who received sclerotherapy (n = 165) were Group A = 20.7%, B = 51% and C = 28.3%; steroids (n = 3): Group A = 100%; beta-blockers (n = 1): Group C = 100%; excision (n = 2): Group A = 100%. Better outcome was noted in smaller-sized lesions and those who required lesser volume of sodium tetradecyl sulfate (STS) injection. Thus, to conclude, the decision regarding the choice and timing of each therapeutic modality should be individualized based on location, size and type of the lesion. The goal of management in these lesions should be to improve the quality of life rather than elimination of the lesion.

Entities:  

Keywords:  Beta-blockers; Hemangioma; Intralesional sclerotherapy; Steroids; Venous malformation

Mesh:

Year:  2017        PMID: 28466404     DOI: 10.1007/s12098-017-2355-8

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  16 in total

Review 1.  Vascular anomalies.

Authors:  J B Mulliken; S J Fishman; P E Burrows
Journal:  Curr Probl Surg       Date:  2000-08       Impact factor: 1.909

Review 2.  Outcomes and complications of sclerotherapy for venous malformations.

Authors:  Yajing Qiu; Hui Chen; Xiaoxi Lin; Xiaojie Hu; Yunbo Jin; Gang Ma
Journal:  Vasc Endovascular Surg       Date:  2013-06-11       Impact factor: 1.089

3.  Propranolol for severe hemangiomas of infancy.

Authors:  Christine Léauté-Labrèze; Eric Dumas de la Roque; Thomas Hubiche; Franck Boralevi; Jean-Benoît Thambo; Alain Taïeb
Journal:  N Engl J Med       Date:  2008-06-12       Impact factor: 91.245

4.  ISSVA classification.

Authors:  Roshni Dasgupta; Steven J Fishman
Journal:  Semin Pediatr Surg       Date:  2014-06-19       Impact factor: 2.754

5.  Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation.

Authors:  M L Bennett; A B Fleischer; S L Chamlin; I J Frieden
Journal:  Arch Dermatol       Date:  2001-09

Review 6.  Propranolol therapy for infantile haemangiomas: review of the literature.

Authors:  A P Zimmermann; S Wiegand; J A Werner; B Eivazi
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2010-02-01       Impact factor: 1.675

7.  Propranolol vs corticosteroids for infantile hemangiomas: a multicenter retrospective analysis.

Authors:  Cynthia J Price; Carol Lattouf; Bertha Baum; Michael McLeod; Lawrence A Schachner; Ana M Duarte; Elizabeth Alvarez Connelly
Journal:  Arch Dermatol       Date:  2011-08-15

8.  Propranolol treatment of infantile hemangioma: clinical and radiologic evaluations.

Authors:  Ahmed A Talaat; Mahmoud S Elbasiouny; Doaa S Elgendy; Tarek F Elwakil
Journal:  J Pediatr Surg       Date:  2012-04       Impact factor: 2.545

Review 9.  The effectiveness of propranolol in treating infantile haemangiomas: a meta-analysis including 35 studies.

Authors:  Yin Lou; Wen-jia Peng; Yi Cao; Dong-sheng Cao; Juan Xie; Hong-hong Li
Journal:  Br J Clin Pharmacol       Date:  2014-07       Impact factor: 4.335

Review 10.  Are 1-2 tablets dangerous? Beta-blocker exposure in toddlers.

Authors:  Jeffrey N Love; Neal Sikka
Journal:  J Emerg Med       Date:  2004-04       Impact factor: 1.484

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  1 in total

1.  Recent Advances and Controversies in Pediatric Surgery.

Authors:  Yogesh Kumar Sarin
Journal:  Indian J Pediatr       Date:  2017-06-14       Impact factor: 1.967

  1 in total

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