Literature DB >> 2846616

Diagnosis and differential diagnosis of progressive lymphoproliferation and malignant lymphoma in persistent active herpesvirus infection.

G R Krueger1, D V Ablashi, S Z Salahuddin, S F Josephs.   

Abstract

Persistent active Epstein-Barr virus (EBV) and human herpesvirus-6 (HHV-6) infections may be accompanied by extensive lymphoproliferative reactions mimicking malignant lymphoma. Such atypical polyclonal lymphoproliferations (APL) can frequently be separated from malignant lymphoma only by detailed immunopathologic and virologic studies. Recommended procedures include immunotyping of lymphoid cells, extensive viral serology, in situ hybridization and Southern blotting for viral DNA, gene rearrangement and DNA ploidy studies. Clear separation of APL from malignant lymphoma is essential for therapeutic planning.

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Year:  1988        PMID： 2846616     DOI： 10.1016/0166-0934(88)90071-7

Source DB:  PubMed          Journal:  J Virol Methods        ISSN： 0166-0934            Impact factor:   2.014


  5 in total

1.  The evidence of human herpesvirus 6 infection in the lymph nodes of Hodgkin's disease.

Authors:  A Maeda; T Sata; H Enzan; K Tanaka; H Wakiguchi; T Kurashige; K Yamanishi; T Kurata
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1993

2.  Gene for the major antigenic structural protein (p100) of human herpesvirus 6.

Authors:  F Neipel; K Ellinger; B Fleckenstein
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

3.  A chronic "postinfectious" fatigue syndrome associated with benign lymphoproliferation, B-cell proliferation, and active replication of human herpesvirus-6.

Authors:  D Buchwald; A S Freedman; D V Ablashi; J L Sullivan; M Caligiuri; D S Weinberg; C G Hall; R L Ashley; C Saxinger; N Balachandran
Journal:  J Clin Immunol       Date:  1990-11       Impact factor: 8.317

Review 4.  Human Herpesvirus 6 and Malignancy: A Review.

Authors:  Eva Eliassen; Emily Lum; Joshua Pritchett; Joseph Ongradi; Gerhard Krueger; John R Crawford; Tuan L Phan; Dharam Ablashi; Stanley David Hudnall
Journal:  Front Oncol       Date:  2018-11-13       Impact factor: 6.244

Review 5.  Lymphoproliferative Syndromes Associated with Human Herpesvirus-6A and Human Herpesvirus-6B.

Authors:  Eva Eliassen; Gerhard Krueger; Mario Luppi; Dharam Ablashi
Journal:  Mediterr J Hematol Infect Dis       Date:  2018-05-01       Impact factor: 2.576
  5 in total

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