Dear Sir,Two cases of double-chambered right ventricle (DCRV) in adult patients have been reported in previous issues of the Journal of Cardiovascular Echography.[12]In DCRV a progressive muscular obstruction divides the right ventricle into two portions. Hypertrophy of the muscular bands separates the proximal high-pressure inlet chamber from the distal low-pressure infundibular chamber.Obstruction is usually progressive with a wide variability of progression rates, and age at presentation may be equally variable.There are three main forms of DCRV:[3] isolated, with associated ventricular septal defect, and with associated subaortic stenosis. A ventricular septal defect is present in >50%–75% of cases and is usually perimembranous, creating a communication between the left ventricle and the proximal high-pressure chamber of the right ventricle. Most of the times the ventricular septal defect is small and tends to a spontaneous closure. When septal defect is due to malalignement, there is a higher tendency toward left ventricular outflow tract obstruction, which is usually due to a discrete subaortic fibromuscular stenosis.Echocardiography can identify and well characterize DCRV, provided that all available projections are used, including subcostal views.[4] Whenever right ventricular hypertrophy is found in an adult patient, a careful examination of the pulmonary and subpulmonary region is advisable. Parasternal short-axis view may not be sufficient for a clear evaluation of the right midventricular region, and even if aliasing is seen with color Doppler, it is not possible to correctly align the ultrasound beam through an infundibular stenosis, which would be too close to the transducer. Therefore, measurement of the intracavitary gradient would be clearly underestimated. The subcostal right oblique view provides the best point of observation for the right ventricle, with optimal visualization of the inlet and infundibular portions. Besides, the ultrasound beam can be correctly aligned through the midventricular region, with a reliable estimation of the peak velocity.When a right midventricular obstruction is found, a warning sign should switch on in the operator's mind, and a careful evaluation of the membranous ventricular septum and the subaortic region should be carried out. Particularly, in the case by Barik,[1] there is no reported septal defect, but in the video of the left heart angiography, there is clearly a small ventricular septal defect, filling with contrast.Moreover, a discrete subaortic fibromuscular ridge may potentially develop even many years after the DCRV is diagnosed. Therefore, the importance of a long-term follow-up is evident, considering that: (1) a small percentage of ventricular septal defect operated in infancy may develop a DCRV after many years, (2) operated DCRV itself may relapse and progress, and (3) associated left ventricular outflow obstruction may appear with late onset.