Literature DB >> 2846517

Distinct mutation sites in prlA suppressor mutant strains of Escherichia coli respond either to suppression of signal peptide mutations or to blockage of staphylokinase processing.

T Sako1, T Iino.   

Abstract

We have cloned and sequenced some prlA mutant alleles of the Escherichia coli secY gene. From the mutation sites determined, it is strongly suggested that distinct regions in the SecY (PrlA) protein are involved in the recognition of different structural features of a signal peptide as it functions.

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Year:  1988        PMID： 2846517      PMCID： PMC211621          DOI： 10.1128/jb.170.11.5389-5391.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  25 in total

1.  Role of amino-terminal positive charge on signal peptide in staphylokinase export across the cytoplasmic membrane of Escherichia coli.

Authors:  T Iino; M Takahashi; T Sako
Journal:  J Biol Chem       Date:  1987-05-25       Impact factor: 5.157

2.  Characterization and in vivo cloning of prlC, a suppressor of signal sequence mutations in Escherichia coli K12.

Authors:  N J Trun; T J Silhavy
Journal:  Genetics       Date:  1987-08       Impact factor: 4.562

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.

Authors:  J Stader; S A Benson; T J Silhavy
Journal:  J Biol Chem       Date:  1986-11-15       Impact factor: 5.157

5.  Evidence for specificity at an early step in protein export in Escherichia coli.

Authors:  C A Kumamoto; J Beckwith
Journal:  J Bacteriol       Date:  1985-07       Impact factor: 3.490

6.  Production of single-stranded plasmid DNA.

Authors:  J Vieira; J Messing
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

7.  A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene.

Authors:  P D Riggs; A I Derman; J Beckwith
Journal:  Genetics       Date:  1988-04       Impact factor: 4.562

8.  secD, a new gene involved in protein export in Escherichia coli.

Authors:  C Gardel; S Benson; J Hunt; S Michaelis; J Beckwith
Journal:  J Bacteriol       Date:  1987-03       Impact factor: 3.490

9.  The SecY membrane component of the bacterial protein export machinery: analysis by new electrophoretic methods for integral membrane proteins.

Authors:  Y Akiyama; K Ito
Journal:  EMBO J       Date:  1985-12-01       Impact factor: 11.598

10.  Topology analysis of the SecY protein, an integral membrane protein involved in protein export in Escherichia coli.

Authors:  Y Akiyama; K Ito
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598
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  27 in total

1.  The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits.

Authors:  F Duong; W Wickner
Journal:  EMBO J       Date:  1999-06-15       Impact factor: 11.598

2.  Cloning and molecular characterization of the secY genes from Bacillus licheniformis and Staphylococcus carnosus: comparative analysis of nine members of the SecY family.

Authors:  S Tschauder; A J Driessen; R Freudl
Journal:  Mol Gen Genet       Date:  1992-10

3.  Characterization of cold-sensitive secY mutants of Escherichia coli.

Authors:  T Baba; A Jacq; E Brickman; J Beckwith; T Taura; C Ueguchi; Y Akiyama; K Ito
Journal:  J Bacteriol       Date:  1990-12       Impact factor: 3.490

Review 4.  The sec and prl genes of Escherichia coli.

Authors:  K L Bieker; G J Phillips; T J Silhavy
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

Review 5.  Structure, function, and biogenesis of SecY, an integral membrane protein involved in protein export.

Authors:  K Ito
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

6.  Streptokinase mutations relieving Escherichia coli K-12 (prlA4) of detriments caused by the wild-type skc gene.

Authors:  J Müller; H Reinert; H Malke
Journal:  J Bacteriol       Date:  1989-04       Impact factor: 3.490

7.  Modeling the effects of prl mutations on the Escherichia coli SecY complex.

Authors:  Margaret A Smith; William M Clemons; Cathrine J DeMars; Ann M Flower
Journal:  J Bacteriol       Date:  2005-09       Impact factor: 3.490

8.  Reconstitution of protein translocation from detergent-solubilized Escherichia coli inverted vesicles: PrlA protein-deficient vesicles efficiently translocate precursor proteins.

Authors:  M Watanabe; C V Nicchitta; G Blobel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

9.  PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation.

Authors:  J P van der Wolk; P Fekkes; A Boorsma; J L Huie; T J Silhavy; A J Driessen
Journal:  EMBO J       Date:  1998-07-01       Impact factor: 11.598

10.  Cloning and characterization of a secY homolog from Chlamydia trachomatis.

Authors:  L Gu; M Remacha; W M Wenman; R Kaul
Journal:  Mol Gen Genet       Date:  1994-05-25
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