Literature DB >> 2846482

Protection of microvasculature in rat brain against late radiation injury by gammaphos.

E D Plotnikova1, M K Levitman, V V Shaposhnikova, J V Koshevoj, L K Eidus.   

Abstract

The ability of the radioprotector gammaphos to modify the development of late vascular changes in rat brain after local irradiation with 25 Gy was investigated by means of angiographic method. A protective effect was seen against late vascular abnormalities. It is suggested that a causative relationship exists between vascular abnormalities, brain necrosis, and radiation mortality after irradiation with moderate doses.

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Year:  1988        PMID: 2846482     DOI: 10.1016/0360-3016(88)90204-0

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  3 in total

1.  Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors.

Authors:  Richard R Copp; Daniel D Peebles; William E Fahl
Journal:  Bioorg Med Chem Lett       Date:  2011-10-13       Impact factor: 2.823

Review 2.  Whole brain radiation-induced cognitive impairment: pathophysiological mechanisms and therapeutic targets.

Authors:  Yong Woo Lee; Hyung Joon Cho; Won Hee Lee; William E Sonntag
Journal:  Biomol Ther (Seoul)       Date:  2012-07       Impact factor: 4.634

Review 3.  Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation.

Authors:  Carsten Nieder; Nicolaus Andratschke; Sabrina T Astner
Journal:  Radiat Oncol       Date:  2007-06-30       Impact factor: 3.481

  3 in total

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