| Literature DB >> 28464503 |
Manuel van Gemmeren1, Marino Börjesson1, Andreu Tortajada1, Shang-Zheng Sun1, Keisho Okura1, Ruben Martin1,2.
Abstract
A switchable site-selective catalytic carboxylation of allylic alcohols has been developed in which CO2 is used with dual roles, both facilitating C-OH cleavage and as a C1 source. This protocol is characterized by its mild reaction conditions, absence of stoichiometric amounts of organometallic reagents, broad scope, and exquisite regiodivergency which can be modulated by the type of ligand employed.Entities:
Keywords: carbon dioxide; cross-coupling; nickel; regioselectivity; synthetic methods
Year: 2017 PMID： 28464503 DOI： 10.1002/anie.201702857
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336