Literature DB >> 28462976

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells.

Pol Sanllehí1, Mireia Casasampere, José-Luis Abad, Gemma Fabriàs, Olga López, Jordi Bujons, Josefina Casas, Antonio Delgado.   

Abstract

New fluorogenic sensors with suitable kinetic parameters and sensitivity have been developed for the determination of sphingosine-1-phosphate lyase activity in cell lysates. The probe RBM148 can be efficiently loaded into cationic liposomes and used to determine S1PL activity in intact cells.

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Year:  2017        PMID： 28462976     DOI： 10.1039/c7cc01659j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  New fluorogenic probes for neutral and alkaline ceramidases.

Authors:  Mireia Casasampere; Núria Bielsa; Daniel Riba; Laura Bassas; Ruijuan Xu; Cungui Mao; Gemma Fabriàs; José-Luis Abad; Antonio Delgado; Josefina Casas
Journal:  J Lipid Res       Date:  2019-03-29       Impact factor: 5.922

Review 2.  Approaches for probing and evaluating mammalian sphingolipid metabolism.

Authors:  Justin M Snider; Chiara Luberto; Yusuf A Hannun
Journal:  Anal Biochem       Date:  2019-03-24       Impact factor: 3.365

3.  Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice.

Authors:  Anabel S De la Garza-Rodea; Steven A Moore; Jesus Zamora-Pineda; Eric P Hoffman; Karishma Mistry; Ashok Kumar; Jonathan B Strober; Piming Zhao; Jung H Suh; Julie D Saba
Journal:  Int J Mol Sci       Date:  2022-07-08       Impact factor: 6.208
  3 in total

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