Kouamé Hubert Yao1, Aristophane Koffi Tanon2, Adjoua Delphine Lagou3, Serge Didier Konan4, Séry Patrick Diopoh4, Fatou Meite4. 1. Service de néphrologie-médecine interne, CHU Treichville, BP V3 Abidjan 01, Abidjan, Cote d'Ivoire. Electronic address: yaohubert@yahoo.fr. 2. Service des maladies infectieuses et tropicales, CHU Treichville, BP V3 Abidjan 01, Abidjan, Cote d'Ivoire. 3. Service de néphrologie, CHU Yopougon, BP 632 Abidjan 21, Abidjan, Cote d'Ivoire. 4. Service de néphrologie-médecine interne, CHU Treichville, BP V3 Abidjan 01, Abidjan, Cote d'Ivoire.
Abstract
BACKGROUND: Acute kidney injury (AKI) is commonly associated with HIV infection. OBJECTIVES: To describe the profile of AKI in HIV infected versus non-infected persons. PATIENTS AND METHODS: This is a prospective study that was carried out during the study period from January 2010 to December 2015 in the department of nephrology-internal medicine D of Treichville University Hospital (Côte d'Ivoire). RESULTS: The prevalence of HIV infection was 35.2% in the population of AKI. The average age of patients was 42±18 years in the HIV positive group against 51±18 years in the HIV negative group (P=0.0001). Etiologies were infections in 65.1% in the HIV positive group against 38.8% in the HIV negative group (P=0.0001) and water loss in 24.7% in the HIV positive group against 7.8% in the HIV negative group (P=0.0001). Factors such as the AIDS stage (P=0.002), severe sepsis (P=0.002) and acute pyelonephritis (P=0.001) were associated with mortality in HIV positive patients against severe anemia (P=0.0001) and severe sepsis (P=0.0001) in the HIV-negative group. CONCLUSION: HIV positive patients are younger with a female predominance. The mortality rate is identical in both groups.
BACKGROUND:Acute kidney injury (AKI) is commonly associated with HIV infection. OBJECTIVES: To describe the profile of AKI in HIV infected versus non-infectedpersons. PATIENTS AND METHODS: This is a prospective study that was carried out during the study period from January 2010 to December 2015 in the department of nephrology-internal medicine D of Treichville University Hospital (Côte d'Ivoire). RESULTS: The prevalence of HIV infection was 35.2% in the population of AKI. The average age of patients was 42±18 years in the HIV positive group against 51±18 years in the HIV negative group (P=0.0001). Etiologies were infections in 65.1% in the HIV positive group against 38.8% in the HIV negative group (P=0.0001) and water loss in 24.7% in the HIV positive group against 7.8% in the HIV negative group (P=0.0001). Factors such as the AIDS stage (P=0.002), severe sepsis (P=0.002) and acute pyelonephritis (P=0.001) were associated with mortality in HIV positive patients against severe anemia (P=0.0001) and severe sepsis (P=0.0001) in the HIV-negative group. CONCLUSION: HIV positive patients are younger with a female predominance. The mortality rate is identical in both groups.