Literature DB >> 2846137

A depolarizing inhibitory postsynaptic potential activated by synaptically released gamma-aminobutyric acid under physiological conditions in rat hippocampal pyramidal cells.

P Perreault1, M Avoli.   

Abstract

We report that CA1 pyramidal neurons of the rat hippocampus respond to high intensity afferent stimulation by generating a late depolarizing potential that typically occurs between the early (fast) inhibitory postsynaptic potential (IPSP) and the late (slow) IPSP. This potential is reminiscent of the response seen after the application of 4-aminopyridine and can be blocked by bicuculline, indicating that GABAA receptors are involved in its generation.

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Year:  1988        PMID： 2846137     DOI： 10.1139/y88-180

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN： 0008-4212            Impact factor:   2.273


  5 in total

1.  Carbonic anhydrase isoform VII acts as a molecular switch in the development of synchronous gamma-frequency firing of hippocampal CA1 pyramidal cells.

Authors:  Eva Ruusuvuori; Hong Li; Kristiina Huttu; J Matias Palva; Sergei Smirnov; Claudio Rivera; Kai Kaila; Juha Voipio
Journal:  J Neurosci       Date:  2004-03-17       Impact factor: 6.167

2.  Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus.

Authors:  C H Davies; S N Davies; G L Collingridge
Journal:  J Physiol       Date:  1990-05       Impact factor: 5.182

3.  Transition to seizures in the isolated immature mouse hippocampus: a switch from dominant phasic inhibition to dominant phasic excitation.

Authors:  M Derchansky; S S Jahromi; M Mamani; D S Shin; A Sik; P L Carlen
Journal:  J Physiol       Date:  2007-11-08       Impact factor: 5.182

4.  Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.

Authors:  X Xie; T G Smart
Journal:  J Physiol       Date:  1993-01       Impact factor: 5.182

5.  The physiological regulation of synaptic inhibition by GABAB autoreceptors in rat hippocampus.

Authors:  C H Davies; G L Collingridge
Journal:  J Physiol       Date:  1993-12       Impact factor: 5.182
  5 in total

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