| Literature DB >> 28461313 |
Soraya Morales-López1, Catiana Dudiuk2,3, Walter Vivot1, Wanda Szusz1, Susana B Córdoba1, Guillermo Garcia-Effron4,3.
Abstract
The echinocandin susceptibilities of 122 Candida glabrata complex strains (including 5 Candida nivariensis and 3 Candida bracarensis strains) were evaluated by microdilution and compared with the results from a molecular tool able to detect FKS mutations. No echinocandin resistance was detected. The PCR results coincide with the MIC data in 99.25% of the cases (1 C. glabrata strain was misidentified as resistant) but were 20 h faster. C. nivariensis FKS genes were sequenced and showed differences with C. glabrataFKS genes.Entities:
Keywords: Candida bracarensis; Candida glabrata species complex; Candida nivariensis; echinocandin resistance; hot spot
Mesh:
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Year: 2017 PMID: 28461313 PMCID: PMC5487631 DOI: 10.1128/AAC.00170-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191