Literature DB >> 2845985

Heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor by parathyroid hormone (PTH) and PTH-like peptide in osteoblast-like cells.

H A Pols1, J P van Leeuwen, J P Schilte, T J Visser, J C Birkenhäger.   

Abstract

1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3) receptor content in cultured osteogenic sarcoma cells (UMR-106) was found to be increased after treatment with both bovine and human PTH and human PTH-like peptide (hPLP). The dose dependent increase of receptors was preceded by a dose dependent stimulation of cAMP production. This suggests a role for cAMP as mediator of the PTH- and hPLP-induced 1,25-(OH)2D3 receptor up-regulation. Furthermore, evidence was obtained that new mRNA and de novo receptor synthesis is involved in this heterologous 1,25-(OH)2D3 receptor up-regulation.

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Year:  1988        PMID： 2845985     DOI： 10.1016/s0006-291x(88)80883-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

1.  Cloning and characterization of the mouse vitamin D receptor promoter.

Authors:  F Jehan; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-16       Impact factor: 11.205

2.  Vitamin D endocrine system and osteoblasts.

Authors:  Marjolein van Driel; Johannes P T M van Leeuwen
Journal:  Bonekey Rep       Date:  2014-02-05

3.  Parathyroid hormone decreases renal vitamin D receptor expression in vivo.

Authors:  Kevin D Healy; Janeen L Vanhooke; Jean M Prahl; Hector F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-15       Impact factor: 11.205

4.  Serum calcium and vitamin D regulate 1,25-dihydroxyvitamin D3 receptor concentration in rat kidney in vivo.

Authors:  M E Sandgren; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

5.  Modulation by epidermal growth factor of the basal 1,25(OH)2D3 receptor level and the heterologous up-regulation of the 1,25(OH)2D3 receptor in clonal osteoblast-like cells.

Authors:  J P van Leeuwen; H A Pols; J P Schilte; T J Visser; J C Birkenhäger
Journal:  Calcif Tissue Int       Date:  1991-07       Impact factor: 4.333

6.  1,25-dihydroxyvitamin D3 and agents that increase intracellular adenosine 3',5'-monophosphate synergistically inhibit fibroblast proliferation.

Authors:  N Saati; A Ravid; U A Liberman; R Koren
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-04       Impact factor: 2.723

Review 7.  Vitamin D and gene networks in human osteoblasts.

Authors:  Jeroen van de Peppel; Johannes P T M van Leeuwen
Journal:  Front Physiol       Date:  2014-04-09       Impact factor: 4.566

8.  The vitamin d receptor and T cell function.

Authors:  Martin Kongsbak; Trine B Levring; Carsten Geisler; Marina Rode von Essen
Journal:  Front Immunol       Date:  2013-06-18       Impact factor: 7.561

9.  The paracrine feedback loop between vitamin D₃ (1,25(OH)₂D₃) and PTHrP in prehypertrophic chondrocytes.

Authors:  Frances C Bach; Kirsten Rutten; Kristyanne Hendriks; Frank M Riemers; Peter Cornelissen; Alain de Bruin; Ger J Arkesteijn; Richard Wubbolts; William A Horton; Louis C Penning; Marianna A Tryfonidou
Journal:  J Cell Physiol       Date:  2014-12       Impact factor: 6.384
  9 in total

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