| Literature DB >> 28458613 |
Linbo Wang1, Thomas S Richardson1, Xiao-Hua Zhou1,2.
Abstract
It is common that in multi-arm randomized trials, the outcome of interest is "truncated by death," meaning that it is only observed or well-defined conditioning on an intermediate outcome. In this case, in addition to pairwise contrasts, the joint inference for all treatment arms is also of interest. Under a monotonicity assumption we present methods for both pairwise and joint causal analyses of ordinal treatments and binary outcomes in presence of truncation by death. We illustrate via examples the appropriateness of our assumptions in different scientific contexts.Entities:
Keywords: Bayesian analysis; Causal inference; Multi-arm trials; Ordinal treatment variable; Principal stratification; Survey incentives
Year: 2016 PMID: 28458613 PMCID: PMC5407214 DOI: 10.1111/rssb.12188
Source DB: PubMed Journal: J R Stat Soc Series B Stat Methodol ISSN: 1369-7412 Impact factor: 4.488