Literature DB >> 28457526

Delayed Diagnoses in Children with Constipation: Multicenter Retrospective Cohort Study.

Stephen B Freedman1, Jonathan Rodean2, Matthew Hall2, Elizabeth R Alpern3, Paul L Aronson4, Harold K Simon5, Samir S Shah6, Jennifer R Marin7, Eyal Cohen8, Rustin B Morse9, Yiannis Katsogridakis3, Jay G Berry10, Mark I Neuman11.   

Abstract

OBJECTIVE: The use of abdominal radiographs contributes to increased healthcare costs, radiation exposure, and potentially to misdiagnoses. We evaluated the association between abdominal radiograph performance and emergency department (ED) revisits with important alternate diagnosis among children with constipation. STUDY
DESIGN: Retrospective cohort study of children aged <18 years diagnosed with constipation at one of 23 EDs from 2004 to 2015. The primary exposure was abdominal radiograph performance. The primary outcome was a 3-day ED revisit with a clinically important alternate diagnosis. RAND/University of California, Los Angeles methodology was used to define whether the revisit was related to the index visit and due to a clinically important condition other than constipation. Regression analysis was performed to identify exposures independently related to the primary outcome.
RESULTS: A total of 65.7% (185 439/282 225) of children with constipation had an index ED visit abdominal radiograph performed. Three-day revisits occurred in 3.7% (10 566/282 225) of children, and 0.28% (784/282 225) returned with a clinically important alternate related diagnosis. Appendicitis was the most common such revisit, accounting for 34.1% of all 3-day clinically important related revisits. Children who had an abdominal radiograph performed were more likely to have a 3-day revisit with a clinically important alternate related diagnosis (0.33% vs 0.17%; difference 0.17%; 95% CI 0.13-0.20). Following adjustment for covariates, abdominal radiograph performance was associated with a 3-day revisit with a clinically important alternate diagnosis (aOR: 1.39; 95% CI 1.15-1.67). Additional characteristics associated with the primary outcome included narcotic (aOR: 2.63) and antiemetic (aOR: 2.35) administration and underlying comorbidities (aOR: 2.52).
CONCLUSIONS: Among children diagnosed with constipation, abdominal radiograph performance is associated with an increased risk of a revisit with a clinically important alternate related diagnosis.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  abdominal; child; constipation; diagnostic errors; diagnostic imaging; emergency service; hematologic tests; hospital; radiography

Mesh:

Year:  2017        PMID: 28457526     DOI: 10.1016/j.jpeds.2017.03.061

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  3 in total

1.  A National Study to Compare Effective Management of Constipation in Children Receiving Concurrent Versus Standard Hospice Care.

Authors:  Lisa C Lindley; Jessica Keim-Malpass; Melanie J Cozad; Jennifer W Mack; Radion Svynarenko; Mary Lou Clark Fornehed; Whitney Stone; Kerri Qualls; Pamela S Hinds
Journal:  J Hosp Palliat Nurs       Date:  2022-02-01       Impact factor: 1.918

2.  Clinical Features and Preventability of Delayed Diagnosis of Pediatric Appendicitis.

Authors:  Kenneth A Michelson; Scott D Reeves; Joseph A Grubenhoff; Andrea T Cruz; Pradip P Chaudhari; Arianna H Dart; Jonathan A Finkelstein; Richard G Bachur
Journal:  JAMA Netw Open       Date:  2021-08-02

3.  Factors Associated With Potentially Missed Diagnosis of Appendicitis in the Emergency Department.

Authors:  Prashant Mahajan; Tanima Basu; Chih-Wen Pai; Hardeep Singh; Nancy Petersen; M Fernanda Bellolio; Samir K Gadepalli; Neil S Kamdar
Journal:  JAMA Netw Open       Date:  2020-03-02
  3 in total

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