Literature DB >> 28456672

Muscle localization of heterotopic ossification following spinal cord injury.

Malte Ohlmeier1, Eduardo M Suero2, Mirko Aach3, Renate Meindl3, Thomas A Schildhauer4, Mustafa Citak3.   

Abstract

BACKGROUND CONTEXT: Heterotopic ossification (HO) is a known complication especially in people with traumatic spinal cord injury (SCI). Although some risk factors have already been described, the pathophysiology of HO is still unknown. The pelvis is the most common region for HO occurrence. However, the prevalence of HO by muscle groups about the hip is not well described.
PURPOSE: To analyze the prevalence of early HO in muscle groups about the hip in 267 patients with SCI. PATIENT SAMPLE: 267 patients with traumatic SCI and pelvic HO.
METHODS: Between January 2001 and December 2014, 267 patients with SCI were treated in our university hospital and were included in the study. Patients were routinely screened for HO using ultrasound. The diagnosis of HO was validated using magnetic resonance imaging (MRI) or computed tomography (CT). The primary outcome measure was the prevalence of HO by muscle groups around the hip. The following muscle groups around the hip were defined: (1) gluteal group, (2) adductor group, (3) iliopsoas group, and (4) deep muscle group. Additionally, the prevalence of concomitant trochanteric bursitis was recorded in all cases.
RESULTS: The gluteal group showed the highest HO prevalence with 55.8%, followed by the deep muscle group with 31.1%. Concomitant trochanteric bursitis was found in 62 patients (23.2%). No association between pelvic trauma and HO development was observed (n=16, 11%).
CONCLUSIONS: The most common muscular location for the occurrence of HO about the hip was the gluteal muscle group. Considering that no laboratory parameters are currently available for screening for HO, highly sensitive ultrasound screening examinations should be routinely performed, with particular attention paid to the gluteal muscles. Additionally, routine range of motion examination for extension and external rotation of the hip joint is warranted.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Brooker classification; Bursitis trochanteric; Classification; Heterotopic ossification; Muscle localization; Spinal cord injury

Mesh:

Year:  2017        PMID: 28456672     DOI: 10.1016/j.spinee.2017.04.021

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  12 in total

Review 1.  Inflammasomes and the IL-1 Family in Bone Homeostasis and Disease.

Authors:  Hsu-Wen Tseng; Selwin Gabriel Samuel; Kate Schroder; Jean-Pierre Lévesque; Kylie A Alexander
Journal:  Curr Osteoporos Rep       Date:  2022-05-14       Impact factor: 5.163

2.  High-frequency spectral ultrasound imaging (SUSI) visualizes early post-traumatic heterotopic ossification (HO) in a mouse model.

Authors:  Kavitha Ranganathan; Xiaowei Hong; David Cholok; Joe Habbouche; Caitlin Priest; Christopher Breuler; Michael Chung; John Li; Arminder Kaura; Hsiao Hsin Sung Hsieh; Jonathan Butts; Serra Ucer; Ean Schwartz; Steven R Buchman; Jan P Stegemann; Cheri X Deng; Benjamin Levi
Journal:  Bone       Date:  2018-02-14       Impact factor: 4.398

3.  Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury.

Authors:  Kylie A Alexander; Hsu-Wen Tseng; Whitney Fleming; Beulah Jose; Marjorie Salga; Irina Kulina; Susan M Millard; Allison R Pettit; François Genêt; Jean-Pierre Levesque
Journal:  Front Immunol       Date:  2019-03-07       Impact factor: 7.561

4.  Incidence and characteristics of heterotopic ossification after spinal cord injury: a single institution study in India.

Authors:  Sushil Chugh; Kurian Zachariah; Santu Ghosh; Nidhi Rawat
Journal:  Spinal Cord Ser Cases       Date:  2019-08-21

5.  Heterotopic Ossification in Orthopaedic and Trauma surgery: A Histopathological Ossification Score.

Authors:  M Ohlmeier; V Krenn; D M Thiesen; N A Sandiford; T Gehrke; M Citak
Journal:  Sci Rep       Date:  2019-12-05       Impact factor: 4.379

6.  Lollipop Sign - Ossification at Wire Ends after Osteosynthesis?

Authors:  Heinz-Lothar Meyer; Manuel Burggraf; Christina Polan; Martin Husen; Marcel Dudda; Max Daniel Kauther
Journal:  J Orthop Case Rep       Date:  2019

Review 7.  Enhanced Spinal Therapy: Extracorporeal Shock Wave Therapy for the Spine.

Authors:  Brian Fiani; Cyrus Davati; Daniel W Griepp; Jason Lee; Elisabeth Pennington; Christina M Moawad
Journal:  Cureus       Date:  2020-10-27

8.  Impact of Heterotopic Ossification on Functional Recovery in Acute Spinal Cord Injury.

Authors:  Steffen Franz; Lukas Rust; Laura Heutehaus; Rüdiger Rupp; Christian Schuld; Norbert Weidner
Journal:  Front Cell Neurosci       Date:  2022-02-09       Impact factor: 5.505

9.  Heterotopic Ossification: A Late Complication From a Chemical Burn.

Authors:  Eric Clayman; Bahar Abbassi; Anthony W Watt; Wyatt G Payne
Journal:  Eplasty       Date:  2018-01-15

Review 10.  The Survey of Cells Responsible for Heterotopic Ossification Development in Skeletal Muscles-Human and Mouse Models.

Authors:  Łukasz Pulik; Bartosz Mierzejewski; Maria A Ciemerych; Edyta Brzóska; Paweł Łęgosz
Journal:  Cells       Date:  2020-05-26       Impact factor: 6.600

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