Literature DB >> 28455614

[Importance of investigation of fetal eyes : Supplement to fetal autopsy].

M C Herwig-Carl1, K U Loeffler2, A M Müller3.   

Abstract

The investigation of fetal eyes is a subspecialty, which is performed by only a few ophthalmic pathologists and pathologists in specialized centers. If a certain fetal syndrome is suspected, the fetal eyes should be removed and submitted for ophthalmic pathological investigation in a specialized center. This can provide additional diagnostic information allowing a final classification of a syndrome and the comprehensive genetic counselling of parents with respect to future pregnancies. This article provides an overview of the histopathological findings in fetal eyes, which are of particular relevance for the pediatric pathological autopsy. In addition, the basic points of ocular development, the preparation of fetal eyes and frequent artifacts are presented.

Entities:  

Keywords:  Additional diagnostic aspects; Artifact; Development; Ophthalmic pathology; Syndrome

Mesh:

Year:  2017        PMID: 28455614     DOI: 10.1007/s00292-017-0289-6

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  39 in total

1.  OCULAR PATHOLOGY OF THE 13-15 TRISOMY SYNDROME.

Authors:  D G COGAN; T KUWABARA
Journal:  Arch Ophthalmol       Date:  1964-08

2.  Anatomy of lens and pathology of cataracts.

Authors:  D G COGAN
Journal:  Exp Eye Res       Date:  1962-06       Impact factor: 3.467

3.  Hematopoiesis in and around the eye.

Authors:  A B REESE; F C BLODI
Journal:  Am J Ophthalmol       Date:  1954-07       Impact factor: 5.258

4.  Observations in the developing human eye regarding Lange's fold.

Authors:  Martina C Herwig; Kathrin M Münstermann; Annette M Müller; Karin U Loeffler
Journal:  Acta Ophthalmol       Date:  2013-08-02       Impact factor: 3.761

5.  Fryns anophthalmia-plus syndrome in an 18-week-old fetus.

Authors:  Caren Jayasinghe; Ulrich Gembruch; Klaus Kuchelmeister; Friederike Körber; Annette M Müller
Journal:  Pediatr Dev Pathol       Date:  2011-06-15

Review 6.  [Routine investigation of foetal eyes--in what way and what for?].

Authors:  M C Herwig; K U Löffler
Journal:  Klin Monbl Augenheilkd       Date:  2014-07-18       Impact factor: 0.700

7.  Surface differentiation of the human corneal epithelium during prenatal development.

Authors:  K Sellheyer; M Spitznas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1988       Impact factor: 3.117

8.  Anophthalmia-microphthalmia-oblique clefting syndrome: confirmation of the Fryns anophthalmia syndrome.

Authors:  M Warburg; H Jensen; J U Prause; S Bolund; F Skovby; M J Miranda
Journal:  Am J Med Genet       Date:  1997-11-28

9.  Morphologic analysis of artifacts in human fetal eyes confounding histopathologic investigations.

Authors:  Martina C Herwig; Annette M Müller; Frank G Holz; Karin U Loeffler
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-04-25       Impact factor: 4.799

10.  Histogenesis of retinal dysplasia in trisomy 13.

Authors:  Ada Chan; Satyan Lakshminrusimha; Reid Heffner; Federico Gonzalez-Fernandez
Journal:  Diagn Pathol       Date:  2007-12-18       Impact factor: 2.644

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