Literature DB >> 28455164

Microvascular complications and their associated risk factors in type 2 diabetes mellitus.

Parvin Akter Khanam1, Sayama Hoque2, Tanjima Begum3, Samira Humaira Habib4, Zafar Ahmed Latif5.   

Abstract

AIMS: The aim of this study was to determine the prevalence of microvascular complications and to identify the various risk factors related to these complications in subjects with diabetes.
MATERIALS AND METHODS: The study was cross-sectional and conducted in Outdoor of BIRDEM, from July 2014 to December 2014. Subjects were considered at age 30 to 60 years and duration of diabetes was 2-10 years. Investigations included socio-demographic, anthropometry and blood pressure. Blood samples were collected for HbA1c, fasting plasma glucose (FBG), 2-h after breakfast (2-hBG), total cholesterol (chol), triglyceride (TG), LDL, HDL, Hb% and serum creatinine. All the complications were taken from the medical record books which was diagnosed by physician.
RESULTS: A total of 400 type 2 diabetes mellitus patients were investigated in this study. The mean and SD of age was 50.05±7.54. The male and female subjects were 41.5% and 58.5% respectively. The prevalence of diabetic retinopathy, nephropathy, neuropathy was 12.3%, 21.3% and 16.8% respectively. Logistic regression model estimated that increasing age (age>50y; OR=3.04; p=<0.001), female participants (OR=1.35; p=<0.04), rural patients (OR=3.75; p=<0.001), housewife (OR=1.89; p=<0.01) and retired patients (2.50; p=<0.03), lack of physical exercise, increasing HbA1c (p=<0.001), FBG (p=<0.001), 2-hBG (<0.001) and blood pressure (p=0.000) had independent significant risk factors for any of three microvascular complications.
CONCLUSION: This study observed that about all the microvascular complications were developed from first three years after registration at BIRDEM. Increasing age, HbA1c, FBG, 2-hBG and blood pressure had significant risk factors for any type of microvascular complications.
Copyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Microvascular complications; Risk factors; Type 2 diabetes mellitus

Mesh:

Substances:

Year:  2017        PMID: 28455164     DOI: 10.1016/j.dsx.2017.04.007

Source DB:  PubMed          Journal:  Diabetes Metab Syndr        ISSN: 1871-4021


  9 in total

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9.  Prevalence of and factors related to microvascular complications in patients with type 2 diabetes mellitus in Tianjin, China: a cross-sectional study.

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  9 in total

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