Literature DB >> 2845388

Characterization of the tumour necrosis factor receptor in human placenta.

D K Eades1, P Cornelius, P H Pekala.   

Abstract

A specific receptor for tumour necrosis factor present in a purified plasma membrane preparation from the villous tissue of human placenta has been characterized. The data fit a one-class-of-sites model exhibiting a KD = 28.4 (+/- 0.002) nM, with 8.1 (+/- 0.05) X 10(11) receptors mg-1 membrane protein. These data provide evidence for the existence of a specific receptor for a major endotoxin-induced cytokine in the placenta.

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Year:  1988        PMID： 2845388     DOI： 10.1016/0143-4004(88)90032-x

Source DB:  PubMed          Journal:  Placenta        ISSN： 0143-4004            Impact factor:   3.481


  5 in total

1.  Localization of tumour necrosis factor production in cells at the materno/fetal interface in human pregnancy.

Authors:  G Vince; S Shorter; P Starkey; J Humphreys; L Clover; T Wilkins; I Sargent; C Redman
Journal:  Clin Exp Immunol       Date:  1992-04       Impact factor: 4.330

2.  Expression and localization of messenger RNA for tumor necrosis factor receptor (TNF-R) I and TNF-RII in pregnant mouse uterus and placenta.

Authors:  K F Roby; N Laham; H Kröning; P F Terranova; J S Hunt
Journal:  Endocrine       Date:  1995-08       Impact factor: 3.633

3.  Low-affinity receptors for tumour necrosis factor-alpha, interferon-gamma and granulocyte-macrophage colony-stimulating factor are expressed on human placental syncytiotrophoblast.

Authors:  J Hampson; P J McLaughlin; P M Johnson
Journal:  Immunology       Date:  1993-07       Impact factor: 7.397

4.  Analysis of p60 and p80 tumor necrosis factor-alpha receptor messenger RNA and protein in human placentas.

Authors:  K K Yelavarthi; J S Hunt
Journal:  Am J Pathol       Date:  1993-10       Impact factor: 4.307

5.  Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestation.

Authors:  H L Chen; Y P Yang; X L Hu; K K Yelavarthi; J L Fishback; J S Hunt
Journal:  Am J Pathol       Date:  1991-08       Impact factor: 4.307
  5 in total

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