| Literature DB >> 28453294 |
Maciej Giedyk1, Joanna Turkowska1, Sandra Lepak1, Marcin Marculewicz1, Keith Ó Proinsias1, Dorota Gryko1.
Abstract
Vitamin B12 is a natural cobalt complex that, while reduced to the "supernucleophilic" Co(I) form, can easily react with electrophiles via an SN2 mechanism. It is also shown to react via an SN2' mechanism with allylic compounds allowing for photochemical deprotection of (allyloxy)arenes. A sustainable alternative to commonly used noble metal-catalyzed deprotection reactions is presented.Entities:
Year: 2017 PMID： 28453294 DOI： 10.1021/acs.orglett.7b01012
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005