| Literature DB >> 28453189 |
Priya Patel1,2, Paula D Robinson3, Jennifer Thackray4, Jacqueline Flank1, Mark T Holdsworth5, Paul Gibson6, Andrea Orsey7,8, Carol Portwine9, Jason Freedman10,11, Jennifer R Madden12, Robert Phillips13,14, Lillian Sung15,16, L Lee Dupuis1,2,16.
Abstract
This update of the 2013 clinical practice guideline provides clinicians with guidance regarding the use of aprepitant and palonosetron for the prevention of acute chemotherapy-induced nausea and vomiting (CINV) in children. The recommendations were based on three systematic reviews. Substantive changes were made to the guideline recommendations including the inclusion of palonosetron to the 5-HT3 antagonists recommended for children receiving highly emetogenic chemotherapy (HEC) and the recommendation of aprepitant for children 6 months of age or older receiving HEC. To optimize CINV control in children, future work must focus on closing critical research gaps.Entities:
Keywords: chemotherapy; guideline; nausea; pediatrics; supportive care; vomiting
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Year: 2017 PMID: 28453189 DOI: 10.1002/pbc.26542
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN: 1545-5009 Impact factor: 3.167