| Literature DB >> 28450384 |
Viviane Slon1, Charlotte Hopfe2, Clemens L Weiß3, Fabrizio Mafessoni2, Marco de la Rasilla4, Carles Lalueza-Fox5, Antonio Rosas6, Marie Soressi7,8, Monika V Knul9, Rebecca Miller10, John R Stewart9, Anatoly P Derevianko11,12, Zenobia Jacobs13,14, Bo Li13, Richard G Roberts13,14, Michael V Shunkov11,15, Henry de Lumley16,17, Christian Perrenoud16,18, Ivan Gušić19, Željko Kućan19, Pavao Rudan19, Ayinuer Aximu-Petri2, Elena Essel2, Sarah Nagel2, Birgit Nickel2, Anna Schmidt2, Kay Prüfer2, Janet Kelso2, Hernán A Burbano3, Svante Pääbo2, Matthias Meyer1.
Abstract
Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.Entities:
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Year: 2017 PMID： 28450384 DOI： 10.1126/science.aam9695
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728