Literature DB >> 28450361

Treat the Patient, Not Just the Cell!

Penelope A Boyden1, Peter J Mohler2.   

Abstract

Entities:  

Keywords:  Purkinje cells; arrhythmias, cardiac; ion channels; muscle cells; therapeutics

Mesh：

Year:  2017        PMID： 28450361      PMCID： PMC5412716          DOI： 10.1161/CIRCRESAHA.116.310427

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


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  11 in total

1.  Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.

Authors:  Tao Yang; Thomas C Atack; Dina Myers Stroud; Wei Zhang; Lynn Hall; Dan M Roden
Journal:  Circ Res       Date:  2012-06-20       Impact factor: 17.367

2.  Functional Nav1.8 channels in intracardiac neurons: the link between SCN10A and cardiac electrophysiology.

Authors:  Arie O Verkerk; Carol Ann Remme; Cees A Schumacher; Brendon P Scicluna; Rianne Wolswinkel; Berend de Jonge; Connie R Bezzina; Marieke W Veldkamp
Journal:  Circ Res       Date:  2012-06-20       Impact factor: 17.367

Review 3.  Genetics of Brugada syndrome.

Authors:  Hiroshi Watanabe; Tohru Minamino
Journal:  J Hum Genet       Date:  2015-07-30       Impact factor: 3.172

Review 4.  The formation and function of the cardiac conduction system.

Authors:  Jan Hendrik van Weerd; Vincent M Christoffels
Journal:  Development       Date:  2016-01-15       Impact factor: 6.868

5.  Long-Term Outcome of Patients Initially Diagnosed With Idiopathic Ventricular Fibrillation: A Descriptive Study.

Authors:  Marloes Visser; Jeroen F van der Heijden; Jasper J van der Smagt; Pieter A Doevendans; Arthur A Wilde; Peter Loh; Rutger J Hassink
Journal:  Circ Arrhythm Electrophysiol       Date:  2016-10

6.  New approaches to antiarrhythmic therapy, Part I: emerging therapeutic applications of the cell biology of cardiac arrhythmias.

Authors: 
Journal:  Circulation       Date:  2001-12-04       Impact factor: 29.690

7.  Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation.

Authors:  Ling Xiao; Tamara T Koopmann; Balázs Ördög; Pieter G Postema; Arie O Verkerk; Vivek Iyer; Kevin J Sampson; Gerard J J Boink; Maya A Mamarbachi; Andras Varro; Luc Jordaens; Jan Res; Robert S Kass; Arthur A Wilde; C R Bezzina; Stanley Nattel
Journal:  Circ Res       Date:  2013-03-26       Impact factor: 17.367

8.  A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel.

Authors:  M C Sanguinetti; C Jiang; M E Curran; M T Keating
Journal:  Cell       Date:  1995-04-21       Impact factor: 41.582

9.  Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.

Authors:  Elijah R Behr; Eleonora Savio-Galimberti; Julien Barc; Anders G Holst; Evmorfia Petropoulou; Bram P Prins; Javad Jabbari; Margherita Torchio; Myriam Berthet; Yuka Mizusawa; Tao Yang; Eline A Nannenberg; Federica Dagradi; Peter Weeke; Rachel Bastiaenan; Michael J Ackerman; Stig Haunso; Antoine Leenhardt; Stefan Kääb; Vincent Probst; Richard Redon; Sanjay Sharma; Arthur Wilde; Jacob Tfelt-Hansen; Peter Schwartz; Dan M Roden; Connie R Bezzina; Morten Olesen; Dawood Darbar; Pascale Guicheney; Lia Crotti; Yalda Jamshidi
Journal:  Cardiovasc Res       Date:  2015-02-17       Impact factor: 10.787

10.  Use of whole exome sequencing for the identification of Ito-based arrhythmia mechanism and therapy.

Authors:  Amy C Sturm; Crystal F Kline; Patric Glynn; Benjamin L Johnson; Jerry Curran; Ahmet Kilic; Robert S D Higgins; Philip F Binkley; Paul M L Janssen; Raul Weiss; Subha V Raman; Steven J Fowler; Silvia G Priori; Thomas J Hund; Cynthia A Carnes; Peter J Mohler
Journal:  J Am Heart Assoc       Date:  2015-05-26       Impact factor: 5.501
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