Literature DB >> 28449824

Primary mucosal melanoma of the palatine tonsil: Report of a case and review of the literature.

Marcela Osorio1, Sami P Moubayed2, Juan Hernandez-Prera3, John C Scott4, Mark L Urken2.   

Abstract

BACKGROUND: Mucosal melanoma of the palatine tonsil is extremely rare. Due to its poor prognosis, primary tonsillar melanoma requires prompt recognition and treatment.
METHODS: A 62-year-old female presented with a deeply pigmented and exophytic lesion in the left tonsillar fossa. The patient underwent a partial pharyngectomy through a midline labio-mandibulotomy approach along with a left level I-V neck dissection. Reconstruction with a left radial forearm free flap and a pharyngeal constrictor advancement pharyngoplasty was performed.
RESULTS: The patient remains free of disease at eight months after adjuvant proton therapy and eleven months after surgery. To our knowledge, less than thirty cases have been either reported or referenced in the literature since the early 1900's. This report is the first in English literature to compile all reported cases of primary tonsillar melanoma.
CONCLUSION: Currently, evidence suggests that mucosal melanoma in the palatine tonsil should be treated in the same fashion as other head and neck mucosal melanomas, mindful of the high rates at which locoregional and distant metastases occur.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Mucosal melanoma; Oropharynx; Palatine tonsil; Primary tonsillar melanoma; Tonsillar melanoma

Mesh:

Year:  2017        PMID: 28449824     DOI: 10.1016/j.amjoto.2017.04.010

Source DB:  PubMed          Journal:  Am J Otolaryngol        ISSN: 0196-0709            Impact factor:   1.808


  2 in total

1.  Extragonadal Non-gestational Choriocarcinoma with Tonsillar Presentation.

Authors:  Thomas Payne; Silvana Di Palma; David Walker; Jonathan Dakin; Lester D R Thompson
Journal:  Head Neck Pathol       Date:  2020-10-31

2.  An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma.

Authors:  Pete J Rae; James E H M Bates; Lisa R Fraser
Journal:  J Surg Case Rep       Date:  2022-02-09
  2 in total

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