Literature DB >> 28449253

Amide-Directed C-H Sodiation by a Sodium Hydride/Iodide Composite.

Yinhua Huang1, Guo Hao Chan1, Shunsuke Chiba1.   

Abstract

A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  C−H activation; amides; arenes; metalation; sodium hydride

Year:  2017        PMID： 28449253     DOI： 10.1002/anie.201702512

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  6 in total

1.  Rhodium-Catalyzed (4+1) Cycloaddition between Benzocyclobutenones and Styrene-Type Alkenes.

Authors:  Shusuke Ochi; Zining Zhang; Ying Xia; Guangbin Dong
Journal:  Angew Chem Int Ed Engl       Date:  2022-03-30       Impact factor: 16.823

2.  Carbonyl 1,2-transposition through triflate-mediated α-amination.

Authors:  Zhao Wu; Xiaolong Xu; Jianchun Wang; Guangbin Dong
Journal:  Science       Date:  2021-11-04       Impact factor: 63.714

3.  LiCl-promoted amination of β-methoxy amides (γ-lactones).

Authors:  Ru Zhao; Bing-Lin Zeng; Wen-Qiang Jia; Hong-Yi Zhao; Long-Ying Shen; Xiao-Jian Wang; Xian-Dao Pan
Journal:  RSC Adv       Date:  2020-09-21       Impact factor: 4.036

4.  Radical Hydrodehalogenation of Aryl Bromides and Chlorides with Sodium Hydride and 1,4-Dioxane.

Authors:  Tobias Hokamp; Abhishek Dewanji; Maximilian Lübbesmeyer; Christian Mück-Lichtenfeld; Ernst-Ulrich Würthwein; Armido Studer
Journal:  Angew Chem Int Ed Engl       Date:  2017-09-19       Impact factor: 15.336

5.  Synthesis of Phenacene-Helicene Hybrids by Directed Remote Metalation.

Authors:  Sindhu Kancherla; Kåre B Jørgensen
Journal:  J Org Chem       Date:  2020-08-26       Impact factor: 4.354

6.  Continuous Flow Sodiation of Substituted Acrylonitriles, Alkenyl Sulfides and Acrylates.

Authors:  Johannes H Harenberg; Niels Weidmann; Konstantin Karaghiosoff; Paul Knochel
Journal:  Angew Chem Int Ed Engl       Date:  2020-11-03       Impact factor: 16.823
  6 in total

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