Literature DB >> 28443206

Estimation of lung cancer burden in Australia, the Philippines, and Singapore: an evaluation of disability adjusted life years.

Suman Morampudi1, Neha Das1, Arun Gowda1, Anand Patil1.   

Abstract

OBJECTIVE: Lung cancer is one of the leading cancers and major causes of cancer mortality worldwide. The economic burden associated with the high mortality of lung cancer is high, which accounts for nearly $180 billion on a global scale in 2008. This paper aims to understand the economic burden of lung cancer in terms of disability adjusted life years (DALY) in Australia, the Philippines, and Singapore.
METHODS: The years of life lost (YLL) and years lost due to disability (YLD) were calculated using the formula developed by Murray and Lopez in 1996 as part of a comprehensive assessment of mortality and disability for diseases, injuries and risk factors in 1990 and projected to 2020. The same formula is represented in the Global Burden of Disease template provided by the World Health Organization. Appropriate assumptions were made when data were unavailable and projections were performed using regression analysis to obtain data for 2015.
RESULTS: The total DALYs due to lung cancer in Australia, the Philippines, and Singapore were 91,695, 38,584, and 12,435, respectively, and the corresponding DALY rates per a population of 1,000 were 4.0, 0.4, and 2.2, respectively, with a discount rate of 3%. When researchers calculated DALYs without the discount rate, the burden of disease increased substantially; the DALYs were 117,438 in Australia, 50,977 in the Philippines, and 16,379 in Singapore. Overall, YLL or premature death accounted for more than 95% of DALYs in these countries.
CONCLUSIONS: Strategies for prevention, early diagnosis, and prompt treatment must be devised for diseases where the major burden is due to mortality.

Entities:  

Keywords:  DALY; DALY rate; Lung cancer; YLD; YLL; burden of disease; discount rate

Year:  2017        PMID: 28443206      PMCID: PMC5365184          DOI: 10.20892/j.issn.2095-3941.2016.0030

Source DB:  PubMed          Journal:  Cancer Biol Med        ISSN: 2095-3941            Impact factor:   4.248


  10 in total

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2.  Singapore's burden of disease and injury 2004.

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3.  Smoking-attributable burden of lung cancer in the Philippines.

Authors:  Ver Luanni Feliciano Bilano; Maridel P Borja; Eduardo L Cruz; Alvin G Tan; Lalaine L Mortera; Paul Ferdinand M Reganit
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4.  Panel on cost-effectiveness in health and medicine.

Authors:  M Gold
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5.  Quantifying the burden of disease: the technical basis for disability-adjusted life years.

Authors:  C J Murray
Journal:  Bull World Health Organ       Date:  1994       Impact factor: 9.408

6.  Cancer and the Philippine Cancer Control Program.

Authors:  Corazon A Ngelangel; Edward H M Wang
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10.  Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.

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  10 in total
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  5 in total

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