Literature DB >> 28441561

Neural Circuits: Reduced Inhibition in Fragile X Syndrome.

Randall M Golovin1, Kendal Broadie2.   

Abstract

The Drosophila Fragile X Syndrome model has long generated insights into this devastating neurological disease state. A recent study of olfactory neural circuitry shows that decreased lateral inhibition onto projection neurons relaying sensory input into higher brain centers causes impaired behavior.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 28441561      PMCID： PMC5734915          DOI： 10.1016/j.cub.2017.03.011

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  20 in total

1.  Intra-neuronal Competition for Synaptic Partners Conserves the Amount of Dendritic Building Material.

Authors:  Stefanie Ryglewski; Fernando Vonhoff; Kathryn Scheckel; Carsten Duch
Journal:  Neuron       Date:  2017-01-26       Impact factor: 17.173

2.  Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory.

Authors:  Caleb A Doll; Kendal Broadie
Journal:  Development       Date:  2015-04-01       Impact factor: 6.868

3.  Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS).

Authors:  Charlotte D'Hulst; Inge Heulens; Judith R Brouwer; Rob Willemsen; Natalie De Geest; Simon P Reeve; Peter P De Deyn; Bassem A Hassan; R Frank Kooy
Journal:  Brain Res       Date:  2008-12-03       Impact factor: 3.252

4.  Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse.

Authors:  Abdeslem El Idrissi; Xiao-Hua Ding; Jason Scalia; Ekkhart Trenkner; W Ted Brown; Carl Dobkin
Journal:  Neurosci Lett       Date:  2004-12-23       Impact factor: 3.046

5.  Correction of fragile X syndrome in mice.

Authors:  Gül Dölen; Emily Osterweil; B S Shankaranarayana Rao; Gordon B Smith; Benjamin D Auerbach; Sumantra Chattarji; Mark F Bear
Journal:  Neuron       Date:  2007-12-20       Impact factor: 17.173

Review 6.  Early olfactory processing in Drosophila: mechanisms and principles.

Authors:  Rachel I Wilson
Journal:  Annu Rev Neurosci       Date:  2013-07-08       Impact factor: 12.449

7.  FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Authors:  Jennifer C Darnell; Sarah J Van Driesche; Chaolin Zhang; Ka Ying Sharon Hung; Aldo Mele; Claire E Fraser; Elizabeth F Stone; Cynthia Chen; John J Fak; Sung Wook Chi; Donny D Licatalosi; Joel D Richter; Robert B Darnell
Journal:  Cell       Date:  2011-07-22       Impact factor: 41.582

8.  Circuit level defects in the developing neocortex of Fragile X mice.

Authors:  J Tiago Gonçalves; James E Anstey; Peyman Golshani; Carlos Portera-Cailliau
Journal:  Nat Neurosci       Date:  2013-06-02       Impact factor: 24.884

9.  Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits.

Authors:  Torrey L S Truszkowski; Eric J James; Mashfiq Hasan; Tyler J Wishard; Zhenyu Liu; Kara G Pratt; Hollis T Cline; Carlos D Aizenman
Journal:  Neural Dev       Date:  2016-08-08       Impact factor: 3.842

10.  Identification of consensus binding sites clarifies FMRP binding determinants.

Authors:  Bart R Anderson; Pankaj Chopra; Joshua A Suhl; Stephen T Warren; Gary J Bassell
Journal:  Nucleic Acids Res       Date:  2016-07-04       Impact factor: 16.971
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  1 in total

1.  Activity-Dependent Remodeling of Drosophila Olfactory Sensory Neuron Brain Innervation during an Early-Life Critical Period.

Authors:  Randall M Golovin; Jacob Vest; Dominic J Vita; Kendal Broadie
Journal:  J Neurosci       Date:  2019-02-12       Impact factor: 6.167
  1 in total

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