| Literature DB >> 28441419 |
Abstract
[This corrects the article DOI: 10.1371/journal.pone.0170674.].Entities:
Year: 2017 PMID: 28441419 PMCID: PMC5404841 DOI: 10.1371/journal.pone.0176772
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 2Gene expression of Runx2, RANKL, Smad3 and ALK5 in rats treated by fluoride with or without SB431542.
Rats was treated with sodium fluoride by gavage at 10 mgF-/kg.bw and 20 mgF-/kg.bw for 2 months, and half of rats in each group were injected with an ALK5 inhibitor (SB431542, 2.1 mg/kg.bw). The femurs were collected and extracted mRNA by Trizol reagent. Realtime PCR was used to analyze Runx2, RANKL, Smad3 and ALK5 expression. Results are expressed as mean± SD(n = 3). (**P < 0.01 compare with control group; aa P < 0.01, compare with two groups).