Literature DB >> 28441308

Factors Associated With the Development of and Revision for Proximal Junctional Kyphosis in 440 Consecutive Adult Spinal Deformity Patients.

Fred H Nicholls1, Junseok Bae2, Alexander A Theologis3, Murat S Eksi3, Christopher P Ames4, Sigurd H Berven3, Shane Burch3, Bobby K Tay3, Vedat Deviren3.   

Abstract

MINI: Proximal junctional kyphosis (PJK) is a common, yet incompletely understood, complication of surgery for adult spinal deformity. We analyzed 440 consecutive adult spinal deformity patients for trends in development of PJK and need for revision surgery. pelvic tilt and thoracic kyphosis were predictive for developing PJK, while radiographic evidence of proximal junctional failure was predictive for proceeding to revision. STUDY
DESIGN: Retrospective review of prospectively collected data.
OBJECTIVE: The aim of this study was to examine which radiographic parameters and surgical strategies are most closely associated with proximal junctional kyphosis (PJK) after adult spinal deformity (ASD) surgery, the need for revision surgery for PJK, and whether these differ based on the upper instrumented vertebra (UIV). SUMMARY OF BACKGROUND DATA: Multiple parameters are considered when planning correction of ASD. Determining which of these factors contribute to the development of and need for revision surgery for PJK presents a challenging problem.
METHODS: Consecutive patients undergoing long fusion to the pelvis with age >18 years, minimum 6-month follow-up, and adequate radiographs for analysis in a single institution between 2003 and 2011 were included. Along with chart review, measurement of proximal junctional angle (PJA), sagittal balance, and pelvic parameters was performed on preoperative, postoperative, and latest follow-up radiographs. Postoperative radiographs were also examined for signs of PJF.
RESULTS: A total of 440 patients with a mean follow-up of 34 months met inclusion criteria, 159 of whom developed PJK (36%), with 65 requiring revision surgery (41%). Higher preoperative pelvic tilt (PT) (P = 0.018) and postoperative thoracic kyphosis (TK) (P ≤ 0.001) were predictive for development of PJK, whereas hooks at UIV were protective (odds ratio [OR] 0.049). In patients who developed PJK, revision was more frequent in younger patients (P = 0.005) with greater postoperative sagittal vertical axis and PJA (P = 0.029, P = 0.018). PJF with spondylolisthesis, fracture, or instrumentation failure at the UIV had the highest ORs for proceeding to a revision (5.1, 1.6, and 2.2, respectively).
CONCLUSION: TK and PT are important indicators of overall rigidity and reference the ability of the spine to compensate for sagittal plane deformity. Special attention should be paid to these characteristics and to the choice of proximal instrumentation when attempting to prevent PJK. Prevention of radiographically evident PJF may hold the key to reducing the need for revision surgery. LEVEL OF EVIDENCE: 3.

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Year:  2017        PMID: 28441308     DOI: 10.1097/BRS.0000000000002209

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  13 in total

1.  The influence of spinal fusion length on proximal junction biomechanics: a parametric computational study.

Authors:  Dominika Ignasiak; Tobias Peteler; Tamás F Fekete; Daniel Haschtmann; Stephen J Ferguson
Journal:  Eur Spine J       Date:  2018-07-23       Impact factor: 3.134

Review 2.  Incidence and risk factors of proximal junctional kyphosis after internal fixation for adult spinal deformity: a systematic evaluation and meta-analysis.

Authors:  Jian Zhao; Kai Chen; Xiao Zhai; Kai Chen; Ming Li; Yanghu Lu
Journal:  Neurosurg Rev       Date:  2020-05-19       Impact factor: 3.042

3.  Proximal junctional kyphosis in adult spinal deformity: a novel predictive index.

Authors:  Jian Zhao; Mingyuan Yang; Yilin Yang; Xin Yin; Changwei Yang; Li Li; Ming Li
Journal:  Eur Spine J       Date:  2018-03-05       Impact factor: 3.134

4.  Comparison of clinical and radiological results of dynamic and rigid instrumentation in degenerative lumbar spinal stenosis.

Authors:  Eyup Varol; Mustafa Umut Etli; Furkan Avci; Cumhur Kaan Yaltirik; Ali Fatih Ramazanoglu; Mehmet Resid Onen; Sait Naderi
Journal:  J Craniovertebr Junction Spine       Date:  2022-09-14

5.  Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area.

Authors:  Lei Yuan; Yan Zeng; Zhongqiang Chen; Weishi Li; Xinling Zhang; Shuo Mai
Journal:  Eur Spine J       Date:  2020-11-19       Impact factor: 3.134

6.  Flexibility of thoracic kyphosis affects postoperative sagittal alignment in adult patients with spinal deformity.

Authors:  Sebastian Decker; Michael Mayer; Axel Hempfing; Lukas Ernstbrunner; Wolfgang Hitzl; Christian Krettek; Heiko Koller
Journal:  Eur Spine J       Date:  2019-12-03       Impact factor: 3.134

7.  Possible factors associated with sagittal malalignment recurrence after pedicle subtraction osteotomy.

Authors:  David Eichler; Yann Philippe Charles; Florent Baldairon; Yves Ntilikina; Erik André Sauleau; Jean-Paul Steib
Journal:  Eur Spine J       Date:  2018-09-21       Impact factor: 3.134

8.  Mechanical Complications in Adult Spine Deformity Surgery: Retrospective Evaluation of Incidence, Clinical Impact and Risk Factors in a Single-Center Large Series.

Authors:  Giuseppe Barone; Fabrizio Giudici; Nicolò Martinelli; Domenico Ravier; Stefano Muzzi; Leone Minoia; Antonino Zagra; Laura Scaramuzzo
Journal:  J Clin Med       Date:  2021-04-21       Impact factor: 4.241

9.  Determinants of Postoperative Spinal Height Change among Adult Spinal Deformity Patients with Long Construct Circumferential Fusion.

Authors:  Colleen Rentenberger; Ichiro Okano; Stephan N Salzmann; Toshiyuki Shirahata; Marie-Jacqueline Reisener; Jennifer Shue; Andrew A Sama; Frank P Cammisa; Federico P Girardi; Alexander P Hughes
Journal:  Asian Spine J       Date:  2020-09-03

10.  The impact of bilateral facetectomy on the instantaneous helical axis of the functional thoracic spinal unit T4-5 during axial rotation.

Authors:  Paul Jonathan Roch; Dominik Saul; Nikolai Wüstefeld; Stefan Spiering; Wolfgang Lehmann; Lukas Weiser; Martin Michael Wachowski
Journal:  Int Biomech       Date:  2021-12
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