Literature DB >> 28438689

Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.

Marcel Klingenberg1, Akiko Matsuda2, Sven Diederichs3, Tushar Patel4.   

Abstract

The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their potential use for the detection and treatment of liver cancer.
Copyright © 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer stem cell; Epithelial–to-mesenchymal transition; HCC; Hepatocellular carcinoma; Liver cancer; Long non-coding RNA; STAT3; Wnt; lncRNA; microRNA

Mesh：

Substances：

Year:  2017        PMID： 28438689     DOI： 10.1016/j.jhep.2017.04.009

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


  150 in total

1.  A novel long noncoding RNA lncWDR26 suppresses the growth and metastasis of hepatocellular carcinoma cells through interaction with SIX3.

Authors:  Baosheng Chen
Journal:  Am J Cancer Res       Date:  2018-04-01       Impact factor: 6.166

2.  MiRNA extraction from cell-free biofluid using protein corona formed around carboxyl magnetic nanoparticles.

Authors:  Shengqiang Xu; Seyedmehdi Hossaini Nasr; Daoyang Chen; Xiaoxian Zhang; Liangliang Sun; Xuefei Huang; Chunqi Qian
Journal:  ACS Biomater Sci Eng       Date:  2017-12-18

3.  Long noncoding RNA expression profiles in chondrogenic and hypertrophic differentiation of mouse mesenchymal stem cells.

Authors:  Zhen Cao; Song Huang; Jianmei Li; Yun Bai; Ce Dou; Chuan Liu; Fei Kang; Xiaoshan Gong; Haibin Ding; Tianyong Hou; Shiwu Dong
Journal:  Funct Integr Genomics       Date:  2017-07-22       Impact factor: 3.410

Review 4.  MicroRNA regulation of liver cancer stem cells.

Authors:  Weiyang Lou; Jingxing Liu; Yanjia Gao; Guansheng Zhong; Bisha Ding; Liang Xu; Weimin Fan
Journal:  Am J Cancer Res       Date:  2018-07-01       Impact factor: 6.166

Review 5.  Epidemiological and etiological variations in hepatocellular carcinoma.

Authors:  Evangelista Sagnelli; Margherita Macera; Antonio Russo; Nicola Coppola; Caterina Sagnelli
Journal:  Infection       Date:  2019-07-25       Impact factor: 3.553

6.  Targeting Hedgehog signalling in CD133-positive hepatocellular carcinoma: improving Lenvatinib therapeutic efficiency.

Authors:  Qingqing Hu; Xiaochu Hu; Lingjian Zhang; Yalei Zhao; Lanjuan Li
Journal:  Med Oncol       Date:  2021-03-17       Impact factor: 3.064

Review 7.  New insights into autophagy in hepatocellular carcinoma: mechanisms and therapeutic strategies.

Authors:  Shuo Yang; Liang Yang; Xinyu Li; Bowen Li; Yan Li; Xiaodong Zhang; Yingbo Ma; Xueqiang Peng; Hongyuan Jin; Hangyu Li
Journal:  Am J Cancer Res       Date:  2019-07-01       Impact factor: 6.166

8.  Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver.

Authors:  Nicholas J Lodato; Tisha Melia; Andy Rampersaud; David J Waxman
Journal:  Toxicol Sci       Date:  2017-09-01       Impact factor: 4.849

9.  Panel of potential lncRNA biomarkers can distinguish various types of liver malignant and benign tumors.

Authors:  Olga Y Burenina; Natalia L Lazarevich; Inna F Kustova; Daria A Shavochkina; Ekaterina A Moroz; Nikolay E Kudashkin; Yuriy I Patyutko; Alexey V Metelin; Eduard F Kim; Dmitry A Skvortsov; Timofei S Zatsepin; Maria P Rubtsova; Olga A Dontsova
Journal:  J Cancer Res Clin Oncol       Date:  2020-09-12       Impact factor: 4.553

10.  LINC00922 promotes the proliferation, migration, invasion and EMT process of liver cancer cells by regulating miR-424-5p/ARK5.

Authors:  Zhiyu Ye; Qikuan He; Qiaona Wang; Yunshou Lin; Kenan Cen; Xiaogang Chen
Journal:  Mol Cell Biochem       Date:  2021-06-07       Impact factor: 3.396
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