| Literature DB >> 2843833 |
F J Hock1, H J Gerhards, G Wiemer, P Usinger, R Geiger.
Abstract
These experiments investigated the effects of the new ACTH4-9 analog ebiratide (Hoe 427) [H-Met(O2)-Glu-His-Phe-D-Lys-Phe-NH-(CH2)8-NH2 X 3 CH3COOH] on memory processes in mice and rats in five training tasks. With all five training and testing procedures (inhibitory avoidance test with ECS- or scopolamine-induced amnesia, up-hill avoidance, one-way shuttle box avoidance and eight-arm radial maze) ebiratide was most effective in a dose range of 1-10 micrograms/kg SC.Entities:
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Year: 1988 PMID： 2843833 DOI： 10.1016/0196-9781(88)90167-2
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750