Literature DB >> 2843686

Duplication of noncoding sequences in polyomavirus specifically augments the development of thymic tumors in mice.

R Freund1, C J Dawe, T L Benjamin.   

Abstract

A 40-base-pair duplication of noncoding sequences in polyomavirus specifically augmented the development of thymic epitheliomas following inoculation of virus into newborn mice. Virus strains carrying only one copy of this sequence induced a full spectrum of tumors except for overt thymic tumors. This 40-base-pair repeat, on the early side of the replication origin, constituted a tissue-specific regulatory determinant for tumor induction.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2843686      PMCID： PMC253541          DOI： 10.1128/JVI.62.10.3896-3899.1988

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  14 in total

1.  The nucleotide sequence and genome organization of the polyoma early region: extensive nucleotide and amino acid homology with SV40.

Authors:  T Friedmann; A Esty; P LaPorte; P Deininger
Journal:  Cell       Date:  1979-07       Impact factor: 41.582

2.  Location of sequences in polyomavirus DNA that are required for early gene expression in vivo and in vitro.

Authors:  C R Mueller; A M Mes-Masson; M Bouvier; J A Hassell
Journal:  Mol Cell Biol       Date:  1984-12       Impact factor: 4.272

3.  Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma.

Authors:  P Herbomel; B Bourachot; M Yaniv
Journal:  Cell       Date:  1984-12       Impact factor: 41.582

4.  Polyoma virus early and late mRNAs in productively infected mouse 3T6 cells.

Authors:  W C Heiser; W Eckhart
Journal:  J Virol       Date:  1982-10       Impact factor: 5.103

5.  Changes in the topography of early region transcription during polyoma virus lytic infection.

Authors:  R G Fenton; C Basilico
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

6.  Determination of sequences at the capped 5' ends of polyoma virus early region transcripts synthesized in vivo and in vitro demonstrates an unusual microheterogeneity.

Authors:  A Cowie; P Jat; R Kamen
Journal:  J Mol Biol       Date:  1982-08-05       Impact factor: 5.469

7.  Coding potential and regulatory signals of the polyoma virus genome.

Authors:  E Soeda; J R Arrand; N Smolar; J E Walsh; B E Griffin
Journal:  Nature       Date:  1980-01-31       Impact factor: 49.962

8.  Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences.

Authors:  B J Pomerantz; J A Hassell
Journal:  J Virol       Date:  1984-03       Impact factor: 5.103

9.  Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA.

Authors:  A Cowie; R Kamen
Journal:  J Virol       Date:  1984-12       Impact factor: 5.103

10.  A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

Authors:  J de Villiers; W Schaffner
Journal:  Nucleic Acids Res       Date:  1981-12-11       Impact factor: 16.971
View more
  14 in total

1.  Tumor induction by a transformation-defective polyoma virus mutant blocked in signaling through Shc.

Authors:  R Bronson; C Dawe; J Carroll; T Benjamin
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-22       Impact factor: 11.205

2.  Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells.

Authors:  Qingsong Qin; Matthew Lauver; Saumya Maru; Eugene Lin; Aron E Lukacher
Journal:  Virology       Date:  2017-01-05       Impact factor: 3.616

3.  Genetic and structural analysis of a virulence determinant in polyomavirus VP1.

Authors:  P H Bauer; R T Bronson; S C Fung; R Freund; T Stehle; S C Harrison; T L Benjamin
Journal:  J Virol       Date:  1995-12       Impact factor: 5.103

4.  Discrimination between sialic acid-containing receptors and pseudoreceptors regulates polyomavirus spread in the mouse.

Authors:  P H Bauer; C Cui; W R Liu; T Stehle; S C Harrison; J A DeCaprio; T L Benjamin
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

5.  Polyomavirus tumor induction in mice: effects of polymorphisms of VP1 and large T antigen.

Authors:  R Freund; A Calderone; C J Dawe; T L Benjamin
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

6.  A single-amino-acid substitution in polyomavirus VP1 correlates with plaque size and hemagglutination behavior.

Authors:  R Freund; R L Garcea; R Sahli; T L Benjamin
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

7.  Polyomavirus replication in mice: influences of VP1 type and route of inoculation.

Authors:  T W Dubensky; R Freund; C J Dawe; T L Benjamin
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

8.  Susceptibility to polyomavirus-induced tumors in inbred mice: role of innate immune responses.

Authors:  Palanivel Velupillai; John P Carroll; Thomas L Benjamin
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

9.  Changes in frequency, morphology, and behavior of tumors induced in mice by a polyoma virus mutant with a specifically altered oncogene.

Authors:  R Freund; C J Dawe; J P Carroll; T L Benjamin
Journal:  Am J Pathol       Date:  1992-12       Impact factor: 4.307

10.  Radiation-resistant and radiation-sensitive forms of host resistance to polyomavirus.

Authors:  J P Carroll; J S Fung; R T Bronson; E Razvi; T L Benjamin
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.