Literature DB >> 28436366

Analysis of preoperative antibiotic prophylaxis in stented, distal hypospadias repair.

Jacob Smith1, Ashay Patel, Ismael Zamilpa, Shasha Bai, Jeffrey Alliston, Stephen Canon.   

Abstract

INTRODUCTION: Surgical site infection [SSI] is a risk for any surgical procedure, including hypospadias repair. Prophylactic antibiotic therapy for patients having surgery is often effective in preventing SSIs, but with increasing rates of antibiotic resistance, this practice has been questioned. The objectives of this study are 1) to assess the incidence of SSIs in patients following stented, distal hypospadias repair and 2) to observe for any potential difference in the incidence of SSIs for patients with and without preoperative antibiotic utilization in this setting.
MATERIALS AND METHODS: We retrospectively reviewed consecutive patients treated with stented, distal hypospadias repair from 2011 to 2014 by three surgeons and compared two groups: patients who received preoperative antibiotics and patients who did not. Patients with a history of previous hypospadias repair were excluded from the study.
RESULTS: Two hundred twenty-four subjects were identified. Group 1 (135) received preoperative antibiotic and Group 2 (89) did not receive preoperative antibiotics. There was no statistically significant difference in SSI prevalence with 0 patients in Group 1 and 1 patient in Group 2 having a SSI.
CONCLUSION: Although prophylactic antibiotics prior to hypospadias repair are most often used by pediatric urologists, this study demonstrates further evidence that antibiotics prior to this procedure do not appear to lower the rate of SSI. This study is limited by its retrospective nature and disparate mean follow up in the two cohorts. Surgical site infection does not appear to be decreased by prophylactic antibiotic therapy before distal hypospadias repair.

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Year:  2017        PMID: 28436366

Source DB:  PubMed          Journal:  Can J Urol        ISSN: 1195-9479            Impact factor:   1.344


  2 in total

1.  Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study.

Authors:  Stephen Canon; Mary K Marquette; Adam Crane; Ashay Patel; Ismael Zamilpa; Shasha Bai
Journal:  Glob Pediatr Health       Date:  2018-04-30

2.  Antimicrobial Prophylaxis for Urologic Procedures in Paediatric Patients: A RAND/UCLA Appropriateness Method Consensus Study in Italy.

Authors:  Susanna Esposito; Erika Rigotti; Alberto Argentiero; Caterina Caminiti; Elio Castagnola; Laura Lancella; Elisabetta Venturini; Maia De Luca; Stefania La Grutta; Mario Lima; Simonetta Tesoro; Matilde Ciccia; Annamaria Staiano; Giovanni Autore; Giorgio Piacentini; Nicola Principi
Journal:  Antibiotics (Basel)       Date:  2022-02-23
  2 in total

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