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Literature DB >> 284362

Incorporation of glucocerebrosidase into Gaucher's disease monocytes in vitro.

Abstract

Several carriers were evaluated for use in the delivery of exogenous glucocerebrosidase to monocytes from Gaucher's disease patients. Only gamma globulin-coated, resealed erythrocytes proved to be an effective vehicle for enzyme delivery. Glucocerebrosidase added in this manner normalized intracellular enzyme levels for at least 18 hr. In this model system for the study of enzyme replacement therapy, soluble enzyme, enzyme in uncoated resealed erythrocytes, and enzyme incorporated into liposomes were ineffective.

Entities: Disease Species

Mesh：

Substances：

Year: 1979 PMID： 284362 PMCID： PMC382963 DOI： 10.1073/pnas.76.1.473

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

19 in total

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Journal: Science Date: 1959-08-21 Impact factor: 47.728

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Authors: C DEDUVE
Journal: Fed Proc Date: 1964 Sep-Oct

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Authors: R O BRADY; J N KANFER; D SHAPIRO
Journal: Biochem Biophys Res Commun Date: 1965-01-18 Impact factor: 3.575

4. Monocyte-derived macrophages: an in vitro system for studying hereditary lysosomal storage diseases.

Authors: S Yatziv; L B Epstein; C J Epstein
Journal: Pediatr Res Date: 1978-09 Impact factor: 3.756

5. Enzyme entrapment in liposomes.

Authors: G Gregoriadis
Journal: Methods Enzymol Date: 1976 Impact factor: 1.600

6. Enzyme replacement therapy in Gaucher's disease: preliminary clinical trial of a new enzyme preparation.

Authors: E Beutler; G L Dale; D E Guinto; W Kuhl
Journal: Proc Natl Acad Sci U S A Date: 1977-10 Impact factor: 11.205

7. Surface marker and other characteristics of Gaucher's cells.

Authors: G F Burns; J C Cawley; R J Flemans; K E Higgy; C P Worman; C R Barker; B E Roberts; F G Hayhoe
Journal: J Clin Pathol Date: 1977-10 Impact factor: 3.411

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Authors: G L Dale; D G Villacorte; E Beutler
Journal: Biochem Med Date: 1977-10

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Authors: P E Belchetz; J C Crawley; I P Braidman; G Gregoriadis
Journal: Lancet Date: 1977-07-16 Impact factor: 79.321

10. Enzyme replacement therapy in Gaucher's disease: a rapid, high-yield method for purification of glucocerebrosidase.

Authors: G L Dale; E Beutler
Journal: Proc Natl Acad Sci U S A Date: 1976-12 Impact factor: 11.205

12 in total

Review 1. Drug delivery by red blood cells: vascular carriers designed by mother nature.

Authors: Vladimir R Muzykantov
Journal: Expert Opin Drug Deliv Date: 2010-04 Impact factor: 6.648

Review 2. Erythrocyte-mediated delivery of recombinant enzymes.

Authors: Vincenzo Leuzzi; Luigia Rossi; Claudia Gabucci; Francesca Nardecchia; Mauro Magnani
Journal: J Inherit Metab Dis Date: 2016-03-30 Impact factor: 4.982

Review 3. Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond.

Authors: Carlos H Villa; Douglas B Cines; Don L Siegel; Vladimir Muzykantov
Journal: Transfus Med Rev Date: 2016-08-17

4. Enhanced binding of phosphatidylserine-containing lipid vesicle targets to RAW264 macrophages.

Authors: D Rimle; W Dereski; H R Petty
Journal: Mol Cell Biochem Date: 1984-09 Impact factor: 3.396

Review 5. Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers.

Authors: Patrick M Glassman; Elizabeth D Hood; Laura T Ferguson; Zongmin Zhao; Don L Siegel; Samir Mitragotri; Jacob S Brenner; Vladimir R Muzykantov
Journal: Adv Drug Deliv Rev Date: 2021-09-29 Impact factor: 15.470

Review 6. Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier.

Authors: Carlos H Villa; Daniel C Pan; Sergei Zaitsev; Douglas B Cines; Donald L Siegel; Vladimir R Muzykantov
Journal: Ther Deliv Date: 2015-07

7. Failure of alglucerase infused into Gaucher disease patients to localize in marrow macrophages.

Authors: E Beutler; W Kuhl; L M Vaughan
Journal: Mol Med Date: 1995-03 Impact factor: 6.354

8. Studies in vivo of the tissue uptake, cellular distribution and catabolic turnover of exogenous glucocerebrosidase in rat.

Authors: S Morrone; P G Pentchev; J Baynes; S Thorpe
Journal: Biochem J Date: 1981-03-15 Impact factor: 3.857

Review 9. Imiglucerase in the treatment of Gaucher disease: a history and perspective.

Authors: Patrick B Deegan; Timothy M Cox
Journal: Drug Des Devel Ther Date: 2012-04-18 Impact factor: 4.162

Review 10. Erythrocytes as Carriers of Therapeutic Enzymes.

Authors: Bridget E Bax
Journal: Pharmaceutics Date: 2020-05-08 Impact factor: 6.321