| Literature DB >> 28435952 |
Yuling Sun1, Yong Tao, Qingchen Cao, Yanbin Huang.
Abstract
Foscarnet sodium is an antiviral drug for the treatment of CMV retinitis, currently in the form of twice-weekly intravitreal injection. Here we developed foscarnet calcium microcrystals as the drug depot, and using the rabbit model we demonstrated that the injected microcrystals maintained a therapeutically relevant drug concentration in the vitreous for more than 3 months.Entities:
Mesh：
Substances：
Year: 2017 PMID： 28435952 DOI： 10.1039/c7cc02399e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222