Literature DB >> 28434084

Population data of 23 autosomal STR loci in the Chinese Han population from Guangdong Province in southern China.

Luyu Yang1,2, Xiufeng Zhang1, Lijuan Zhao3, Yanan Sun4, Jiajue Li5, Renwu Huang5, Liping Hu6, Shengjie Nie7.   

Abstract

The genetic polymorphisms of 23 autosomal short tandem repeat (STR) loci included in the HuaxiaTM Platinum kit were evaluated in 1533 unrelated healthy Guangdong Han individuals living in the Guangdong Province in southern China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine the allele frequencies and forensic statistical parameters. The genetic relationship between the Guangdong Han and other Chinese populations was also estimated. The combined discrimination power and the probability of excluding the paternity of 23 STR loci were 0.999 999 999 999 999 999 999 999 999 74 and 0.999 999 999 72, respectively. These results suggested that the 23 STR loci are highly polymorphic and suitable for personal forensic identification and paternity testing.

Keywords:  Genetic distribution; Guangdong Han; Short tandem repeat (STR); Southern China

Mesh:

Year:  2017        PMID: 28434084     DOI: 10.1007/s00414-017-1588-4

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


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