Literature DB >> 2843323

A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures.

G R Sutherland1, E Baker, D F Callen.   

Abstract

Chromosomes prepared from EBV-transformed lymphoblastoid cell lines show an achromatic gap or fragile site-like lesion at 11q23.1. The low spontaneous expression of this lesion is greatly enhanced by BrdU and n-butyric acid. The lesion was expressed homozygously in all 16 cell lines examined. It is suggested that the lesion is a viral chromosome modification site.

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Year:  1988        PMID: 2843323     DOI: 10.1159/000132549

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  1 in total

1.  Cell type-dependent difference in the distribution and frequency of aphidicolin-induced fragile sites: T and B lymphocytes and bone marrow cells.

Authors:  I Murano; A Kuwano; T Kajii
Journal:  Hum Genet       Date:  1989-12       Impact factor: 4.132

  1 in total

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