Literature DB >> 28433170

Structural characterization and immuno-enhancing activity of a highly branched water-soluble β-glucan from the spores of Ganoderma lucidum.

Yatao Wang1, Yanfang Liu2, Huazheng Yu3, Shuai Zhou4, Zhong Zhang5, Di Wu6, Mengqiu Yan7, Qingjiu Tang8, Jingsong Zhang9.   

Abstract

A water soluble β-glucan (GLSWA-I) with a weight average molecular weight ∼1.57×105g/mol, isolated from the aqueous extract of the broken cellular wall Ganoderma lucidum spores, was purified by anion-exchange and gel-permeation chromatography. The immunological activity test in vivo showed that GLSWA-I could significantly promote dinitrochlorobenzene (DNCB) induced delayed-type ear swelling in mice. Based on the monosaccharides composition analysis, methylation analysis, IR, 1D and 2D NMR spectroscopy, the repeating unit of polysaccharide GLSWA-I was elucidated as follows.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Ganoderma lucidum; Immunological activity; Spores; Structure; β-glucan

Mesh:

Substances:

Year:  2017        PMID: 28433170     DOI: 10.1016/j.carbpol.2017.03.016

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN: 0144-8617            Impact factor:   9.381


  7 in total

1.  Antidepressant-like effect of Ganoderma lucidum spore polysaccharide-peptide mediated by upregulation of prefrontal cortex brain-derived neurotrophic factor.

Authors:  Shuang Zhao; Chengbo Rong; Yi Gao; Linfeng Wu; Xiaoheng Luo; Shuang Song; Yu Liu; Jack Ho Wong; Hexiang Wang; Litao Yi; Tzibun Ng
Journal:  Appl Microbiol Biotechnol       Date:  2021-10-30       Impact factor: 4.813

2.  Structural characterization and hepatoprotective activity of an acidic polysaccharide from Ganoderma lucidum.

Authors:  Shaodan Chen; Xiaoying Guan; Tianqiao Yong; Xiong Gao; Chun Xiao; Yizhen Xie; Diling Chen; Huiping Hu; Qingping Wu
Journal:  Food Chem X       Date:  2022-01-03

3.  TCMIO: A Comprehensive Database of Traditional Chinese Medicine on Immuno-Oncology.

Authors:  Zhihong Liu; Chuipu Cai; Jiewen Du; Bingdong Liu; Lu Cui; Xiude Fan; Qihui Wu; Jiansong Fang; Liwei Xie
Journal:  Front Pharmacol       Date:  2020-04-15       Impact factor: 5.810

4.  Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.

Authors:  Ming Song; Zhen-Hao Li; Hong-Shun Gu; Ru-Ying Tang; Rui Zhang; Ying-Li Zhu; Jin-Lian Liu; Jian-Jun Zhang; Lin-Yuan Wang
Journal:  J Immunol Res       Date:  2021-03-05       Impact factor: 4.818

5.  Polysaccharides from Spores of Cordyceps cicadae Protect against Cyclophosphamide-Induced Immunosuppression and Oxidative Stress in Mice.

Authors:  Yi Zheng; Shiying Li; Chuang Li; Ying Shao; Anhui Chen
Journal:  Foods       Date:  2022-02-11

6.  Research on Extraction, Structure Characterization and Immunostimulatory Activity of Cell Wall Polysaccharides from Sparassis latifolia.

Authors:  Jing Liu; Xuemeng Zhang; Jingsong Zhang; Mengqiu Yan; Deshun Li; Shuai Zhou; Jie Feng; Yanfang Liu
Journal:  Polymers (Basel)       Date:  2022-01-28       Impact factor: 4.329

7.  Extraction, Structural Characterization, and Immunomodulatory Activity of a High Molecular Weight Polysaccharide From Ganoderma lucidum.

Authors:  Guo Liu; Jun Zhang; Qixin Kan; Mingyue Song; Tao Hou; Siyu An; Hongyu Lin; Hongzhang Chen; Liuyun Hu; Jie Xiao; Yunjiao Chen; Yong Cao
Journal:  Front Nutr       Date:  2022-03-25
  7 in total

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