Literature DB >> 28432616

Prognostic impact of PD-1 and its ligands in renal cell carcinoma.

Franziska Erlmeier1,2, Wilko Weichert3,4, Andres Jan Schrader5,6, Michael Autenrieth7, Arndt Hartmann5,8, Sandra Steffens5,6, Philipp Ivanyi9.   

Abstract

Programmed death-1 receptor (PD-1) and programmed death-1 receptor-ligand (PD-L1) have been suggested to play a role as prognostic markers in clear cell renal cell carcinoma (ccRCC). The association between PD-L1 and prognosis seems to be more robust than for PD-1. Further, preliminary analyses suggest that neither PD-1 nor its ligands play a role as prognostic markers in non-clear cell RCC, while the prognostic role of PD-L2 in ccRCC as well as in non-clear cell RCC remains unclear.

Entities:  

Keywords:  PD-1; PD-L1; PD-L2; Prognostic impact; Renal cell carcinoma

Mesh:

Substances:

Year:  2017        PMID: 28432616     DOI: 10.1007/s12032-017-0961-y

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  26 in total

1.  Do programmed death 1 (PD-1) and its ligand (PD-L1) play a role in patients with non-clear cell renal cell carcinoma?

Authors:  Mahmoud Abbas; Sandra Steffens; Maria Bellut; Jan U Becker; Anika Großhennig; Hendrik Eggers; Gerd Wegener; Markus A Kuczyk; Hans H Kreipe; Viktor Grünwald; Andres J Schrader; Philipp Ivanyi
Journal:  Med Oncol       Date:  2016-05-10       Impact factor: 3.064

2.  Clinicopathologic Analysis of PD-L1 and PD-L2 Expression in Renal Cell Carcinoma: Association with Oncogenic Proteins Status.

Authors:  Su-Jin Shin; Yoon Kyung Jeon; Pil-Jong Kim; Yong Mee Cho; Jaemoon Koh; Doo Hyun Chung; Heounjeong Go
Journal:  Ann Surg Oncol       Date:  2016-02       Impact factor: 5.344

3.  PD-L2: A prognostic marker in chromophobe renal cell carcinoma?

Authors:  Franziska Erlmeier; Wilko Weichert; Michael Autenrieth; Max Wiedemann; Andres Jan Schrader; Arndt Hartmann; Philipp Ivanyi; Sandra Steffens
Journal:  Med Oncol       Date:  2017-03-28       Impact factor: 3.064

4.  Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

Authors:  R Houston Thompson; Susan M Kuntz; Bradley C Leibovich; Haidong Dong; Christine M Lohse; W Scott Webster; Shomik Sengupta; Igor Frank; Alexander S Parker; Horst Zincke; Michael L Blute; Thomas J Sebo; John C Cheville; Eugene D Kwon
Journal:  Cancer Res       Date:  2006-04-01       Impact factor: 12.701

5.  PD-1/PD-L1 expression in chromophobe renal cell carcinoma: An immunological exception?

Authors:  Franziska Erlmeier; Arndt Hartmann; Michael Autenrieth; Max Wiedemann; Philipp Ivanyi; Sandra Steffens; Wilko Weichert
Journal:  Med Oncol       Date:  2016-09-30       Impact factor: 3.064

6.  Human chromophobe cell renal carcinoma.

Authors:  W Thoenes; S Störkel; H J Rumpelt
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1985

7.  PD-L1 expression in nonclear-cell renal cell carcinoma.

Authors:  T K Choueiri; A P Fay; K P Gray; M Callea; T H Ho; L Albiges; J Bellmunt; J Song; I Carvo; M Lampron; M L Stanton; F S Hodi; D F McDermott; M B Atkins; G J Freeman; M S Hirsch; S Signoretti
Journal:  Ann Oncol       Date:  2014-09-05       Impact factor: 32.976

8.  The Fuhrman grading system has no prognostic value in patients with nonsarcomatoid chromophobe renal cell carcinoma.

Authors:  Sandra Steffens; Martin Janssen; Frederik C Roos; Frank Becker; Julie Steinestel; Mahmoud Abbas; Konrad Steinestel; Gerd Wegener; Stefan Siemer; Joachim W Thüroff; Rainer Hofmann; Michael Stöckle; Mark Schrader; Arndt Hartmann; Andrea Hasenfus; Markus A Kuczyk; Kerstin Junker; Andres J Schrader
Journal:  Hum Pathol       Date:  2014-08-23       Impact factor: 3.466

9.  PD-L1 expression in papillary renal cell carcinoma.

Authors:  Takanobu Motoshima; Yoshihiro Komohara; Chaoya Ma; Arni Kusuma Dewi; Hirotsugu Noguchi; Sohsuke Yamada; Toshiyuki Nakayama; Shohei Kitada; Yoshiaki Kawano; Wataru Takahashi; Masaaki Sugimoto; Motohiro Takeya; Naohiro Fujimoto; Yoshinao Oda; Masatoshi Eto
Journal:  BMC Urol       Date:  2017-01-13       Impact factor: 2.264

10.  Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Authors:  Y Ishida; Y Agata; K Shibahara; T Honjo
Journal:  EMBO J       Date:  1992-11       Impact factor: 11.598

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  5 in total

Review 1.  [Chromophobe renal cell carcinoma-diagnosis and prognosis].

Authors:  F Erlmeier
Journal:  Pathologe       Date:  2019-12       Impact factor: 1.011

2.  PD-1 Expression and its Correlation With Prognosis in Clear Cell Renal Cell Carcinoma.

Authors:  Min Hye Kim; Gyung Hyuk Ko; Jeong Hee Lee; Jong Sil Lee; Dong Chul Kim; Jung Wook Yang; Hyo Jung An; Ji Min Na; Dae Hyun Song
Journal:  In Vivo       Date:  2021 May-Jun       Impact factor: 2.155

3.  Response to nivolumab in metastatic collecting duct carcinoma expressing PD-L1: A case report.

Authors:  Kosuke Mizutani; Kengo Horie; Shingo Nagai; Tomohiro Tsuchiya; Chiemi Saigo; Kazuhiro Kobayashi; Tatsuhiko Miyazaki; Takashi Deguchi
Journal:  Mol Clin Oncol       Date:  2017-10-12

4.  APOA1 mRNA and protein in kidney renal clear cell carcinoma correlate with the disease outcome.

Authors:  Wei Zeng; Guoguang Xiong; Li Hua; Yugang Hu; Xufeng Guo; Xiulan Peng
Journal:  Sci Rep       Date:  2022-07-20       Impact factor: 4.996

5.  Prognostic and Predictive Value of Tumor-infiltrating Leukocytes and of Immune Checkpoint Molecules PD1 and PDL1 in Clear Cell Renal Cell Carcinoma.

Authors:  Philipp J Stenzel; Mario Schindeldecker; Katrin E Tagscherer; Sebastian Foersch; Esther Herpel; Markus Hohenfellner; Gencay Hatiboglu; Juergen Alt; Christian Thomas; Axel Haferkamp; Wilfried Roth; Stephan Macher-Goeppinger
Journal:  Transl Oncol       Date:  2019-12-24       Impact factor: 4.243

  5 in total

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