Literature DB >> 28432394

[Vitamin D and UV protection].

H Stege1, T Schwarz2.   

Abstract

A high percentage of people present with reduced vitamin D3 levels. Reduced vitamin D3 levels have to be supplemented. Oral supplementation can be performed easily and without significant side effects. Because vitamin D3 can be produced in the skin via ultraviolet B (UVB) irradiation, it is possible to elevate reduced vitamin D3 levels by UVB exposure. However, UVB, which is classified as a complete carcinogen, induces skin cancer. Therefore, UVB irradiation should not be utilized to stimulate vitamin D3 synthesis. Sun protection, especially wearing of clothes and seeking shade and appropriate use of sunscreens, correlates with reduced D3 levels. A risk-benefit calculation shows that oral supplementation of vitamin D3 is preferred to UVB/sun expsure to increase serum vitamin D3 levels.

Entities:  

Keywords:  Carcinogen; Skin cancer; Sun exposure; Supplementation; UVB

Mesh:

Substances:

Year:  2017        PMID: 28432394     DOI: 10.1007/s00105-017-3982-8

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  13 in total

1.  Recommended summer sunlight exposure levels can produce sufficient (> or =20 ng ml(-1)) but not the proposed optimal (> or =32 ng ml(-1)) 25(OH)D levels at UK latitudes.

Authors:  Lesley E Rhodes; Ann R Webb; Heather I Fraser; Richard Kift; Marie T Durkin; Donald Allan; Sarah J O'Brien; Andy Vail; Jacqueline L Berry
Journal:  J Invest Dermatol       Date:  2010-01-14       Impact factor: 8.551

2.  A review of human carcinogens--part D: radiation.

Authors:  Fatiha El Ghissassi; Robert Baan; Kurt Straif; Yann Grosse; Béatrice Secretan; Véronique Bouvard; Lamia Benbrahim-Tallaa; Neela Guha; Crystal Freeman; Laurent Galichet; Vincent Cogliano
Journal:  Lancet Oncol       Date:  2009-08       Impact factor: 41.316

3.  UVB-induced conversion of 7-dehydrocholesterol to 1alpha,25-dihydroxyvitamin D3 in an in vitro human skin equivalent model.

Authors:  B Lehmann; T Genehr; P Knuschke; J Pietzsch; M Meurer
Journal:  J Invest Dermatol       Date:  2001-11       Impact factor: 8.551

4.  Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance.

Authors:  D Albanes; O P Heinonen; P R Taylor; J Virtamo; B K Edwards; M Rautalahti; A M Hartman; J Palmgren; L S Freedman; J Haapakoski; M J Barrett; P Pietinen; N Malila; E Tala; K Liippo; E R Salomaa; J A Tangrea; L Teppo; F B Askin; E Taskinen; Y Erozan; P Greenwald; J K Huttunen
Journal:  J Natl Cancer Inst       Date:  1996-11-06       Impact factor: 13.506

5.  Sun protective behaviors and vitamin D levels in the US population: NHANES 2003-2006.

Authors:  Eleni Linos; Elizabeth Keiser; Matthew Kanzler; Kristin L Sainani; Wayne Lee; Eric Vittinghoff; Mary-Margaret Chren; Jean Y Tang
Journal:  Cancer Causes Control       Date:  2011-11-02       Impact factor: 2.506

6.  [Epidemiological study on the dimension of vitamin D deficiency in North Germany].

Authors:  J Kramer; A Diehl; H Lehnert
Journal:  Dtsch Med Wochenschr       Date:  2014-02-25       Impact factor: 0.628

7.  Regular sunscreen use is a cost-effective approach to skin cancer prevention in subtropical settings.

Authors:  Louisa G Gordon; Paul A Scuffham; Jolieke C van der Pols; Penelope McBride; Gail M Williams; Adèle C Green
Journal:  J Invest Dermatol       Date:  2009-06-18       Impact factor: 8.551

Review 8.  25 years of UV-induced immunosuppression mediated by T cells-from disregarded T suppressor cells to highly respected regulatory T cells.

Authors:  Thomas Schwarz
Journal:  Photochem Photobiol       Date:  2008 Jan-Feb       Impact factor: 3.421

Review 9.  The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis.

Authors:  Mark J Bolland; Andrew Grey; Greg D Gamble; Ian R Reid
Journal:  Lancet Diabetes Endocrinol       Date:  2014-01-24       Impact factor: 32.069

10.  Sun Exposure Guidelines and Serum Vitamin D Status in Denmark: The StatusD Study.

Authors:  Louise Hansen; Anne Tjønneland; Brian Køster; Christine Brot; Rikke Andersen; Marika Lundqvist; Jane Christensen; Anja Olsen
Journal:  Nutrients       Date:  2016-05-05       Impact factor: 5.717

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  1 in total

1.  A systematic review and meta-analysis of the response of serum 25-hydroxyvitamin D concentration to vitamin D supplementation from RCTs from around the globe.

Authors:  Minjia Mo; Shijie Wang; Zun Chen; Xiamusiye Muyiduli; Shuojia Wang; Yu Shen; Bule Shao; Minchao Li; Danqing Chen; Zexin Chen; Yunxian Yu
Journal:  Eur J Clin Nutr       Date:  2019-03-14       Impact factor: 4.016

  1 in total

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