Literature DB >> 2843187

Structure of a novel human granulocyte peptide with anti-ACTH activity.

A Singh1, A Bateman, Q Z Zhu, S Shimasaki, F Esch, S Solomon.   

Abstract

We report the purification, structure and biological properties of a peptide of novel sequence from human granulocytes that inhibits ACTH stimulated synthesis of corticosterone in rat adrenal cell suspensions. The peptide HP-4 is homologous to a previously described human granulocyte peptide HP-1 that has no anti-ACTH activity.

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Year:  1988        PMID： 2843187     DOI： 10.1016/s0006-291x(88)81118-5

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  17 in total

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Review 2.  [Cortisone substitution in sepsis. Is less more?].

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Review 3.  Defensins: microbicidal and cytotoxic peptides of mammalian host defense cells.

Authors:  T Ganz; A Oren; R I Lehrer
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Review 9.  [Corticosteroid insufficiency in the critically ill. Pathomechanisms and recommendations for diagnosis and treatment].

Authors:  J Briegel; M Vogeser; D Keh; P Marik
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10.  Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series.

Authors:  Y Date; M Nakazato; K Shiomi; H Toshimori; K Kangawa; H Matsuo; S Matsukura
Journal:  Ann Hematol       Date:  1994-08       Impact factor: 3.673
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