Alain Lekoubou1, Bruce Ovbiagele2, Daniela Markovic3, Nerses Sanossian4, Amytis Towfighi5. 1. Department of Neurology, Medical University of South Carolina, Charleston, SC, United States. Electronic address: lekoubou@musc.edu. 2. Department of Neurology, Medical University of South Carolina, Charleston, SC, United States. 3. Department of Biomathematics, University of California at Los Angeles, Los Angeles, CA, United States. 4. Department of Neurology, University of Southern California, Los Angeles, CA, United States. 5. Department of Neurology, University of Southern California, Los Angeles, CA, United States; Department of Neurology, Rancho Los Amigos National Rehabilitation Center, Downey, CA, United States.
Abstract
INTRODUCTION: Metabolic syndrome (MetS), an independent risk factor for myocardial infarction (MI) and stroke, affects 1 in 3 adults in the United States. Recent trends in MetS prevalence among MI and stroke survivors are unknown. METHODS: We assessed age, sex, race/ethnicity, and socio-economic status specific trends in rates of MetS among adults ≥18years who participated in National Health and Nutrition Examination Surveys 1999-2010 and who fasted for 8h (n=12,502). MetS was defined using the 2009 harmonized definition. MI and stroke were defined by self-reported diagnosis by a health care provider. RESULTS: MetS prevalence was 65.8% (2.2%) in MI survivors (n=663) and 61.2% (3.8%) in stroke survivors (299). Women aged 35 to 64years with prior MI were more likely to have MetS compared to similarly aged stroke survivors (unadjusted OR 3.13, 95% CI 1.38-7.10). MetS prevalence among MI/stroke survivors remained flat from 1999 to 2010 in all groups except non-Hispanic blacks with prior MI, in whom prevalence increased. From 1999 to 2010, dyslipidemia declined and abdominal obesity and hyperglycemia increased among individuals with prior MI. MetS components remained unchanged among those with prior stroke. CONCLUSION: The persistent high prevalence of MetS among stroke and MI survivors highlights the need for more effective interventions. Published by Elsevier B.V.
INTRODUCTION:Metabolic syndrome (MetS), an independent risk factor for myocardial infarction (MI) and stroke, affects 1 in 3 adults in the United States. Recent trends in MetS prevalence among MI and stroke survivors are unknown. METHODS: We assessed age, sex, race/ethnicity, and socio-economic status specific trends in rates of MetS among adults ≥18years who participated in National Health and Nutrition Examination Surveys 1999-2010 and who fasted for 8h (n=12,502). MetS was defined using the 2009 harmonized definition. MI and stroke were defined by self-reported diagnosis by a health care provider. RESULTS: MetS prevalence was 65.8% (2.2%) in MI survivors (n=663) and 61.2% (3.8%) in stroke survivors (299). Women aged 35 to 64years with prior MI were more likely to have MetS compared to similarly aged stroke survivors (unadjusted OR 3.13, 95% CI 1.38-7.10). MetS prevalence among MI/stroke survivors remained flat from 1999 to 2010 in all groups except non-Hispanic blacks with prior MI, in whom prevalence increased. From 1999 to 2010, dyslipidemia declined and abdominal obesity and hyperglycemia increased among individuals with prior MI. MetS components remained unchanged among those with prior stroke. CONCLUSION: The persistent high prevalence of MetS among stroke and MI survivors highlights the need for more effective interventions. Published by Elsevier B.V.
Entities:
Keywords:
Metabolic syndrome; Myocardial infarction; Stroke; Trends; United States