Literature DB >> 28429767

Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential.

Owen Conway1, Vladimir Kirkin1.   

Abstract

The multimodular adapter p62/sequestosome-1 plays prominent roles in physiology and disease by mediating cell signaling and cargo degradation. The work by Peng et al. published recently in Cell Research provides mechanistic insights into activation of its autophagy receptor function critical for maintaining cell homeostasis during various forms of stress.

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Year:  2017        PMID： 28429767      PMCID： PMC5520859          DOI： 10.1038/cr.2017.56

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  11 in total

1.  Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

Authors:  Gen Matsumoto; Koji Wada; Misako Okuno; Masaru Kurosawa; Nobuyuki Nukina
Journal:  Mol Cell       Date:  2011-10-21       Impact factor: 17.970

2.  Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression.

Authors:  Zhengzhao Liu; Peng Chen; Hong Gao; Yu Gu; Jiao Yang; Hong Peng; Xingxing Xu; Haifeng Wang; Meiqiang Yang; Xiaoying Liu; Libin Fan; Shiyao Chen; Jian Zhou; Yihong Sun; Kangchen Ruan; Shuqun Cheng; Masaaki Komatsu; Eileen White; Lin Li; Hongbin Ji; Daniel Finley; Ronggui Hu
Journal:  Cancer Cell       Date:  2014-07-14       Impact factor: 31.743

3.  The selective autophagy receptor p62 forms a flexible filamentous helical scaffold.

Authors:  Rodolfo Ciuffa; Trond Lamark; Abul K Tarafder; Audrey Guesdon; Sofia Rybina; Wim J H Hagen; Terje Johansen; Carsten Sachse
Journal:  Cell Rep       Date:  2015-04-23       Impact factor: 9.423

4.  Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin.

Authors:  Shin Isogai; Daichi Morimoto; Kyohei Arita; Satoru Unzai; Takeshi Tenno; Jun Hasegawa; Yu-shin Sou; Masaaki Komatsu; Keiji Tanaka; Masahiro Shirakawa; Hidehito Tochio
Journal:  J Biol Chem       Date:  2011-06-29       Impact factor: 5.157

5.  Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.

Authors:  Hong Peng; Jiao Yang; Guangyi Li; Qing You; Wen Han; Tianrang Li; Daming Gao; Xiaoduo Xie; Byung-Hoon Lee; Juan Du; Jian Hou; Tao Zhang; Hai Rao; Ying Huang; Qinrun Li; Rong Zeng; Lijian Hui; Hongyan Wang; Qin Xia; Xuemin Zhang; Yongning He; Masaaki Komatsu; Ivan Dikic; Daniel Finley; Ronggui Hu
Journal:  Cell Res       Date:  2017-03-21       Impact factor: 25.617

Review 6.  Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.

Authors:  Vladimir Rogov; Volker Dötsch; Terje Johansen; Vladimir Kirkin
Journal:  Mol Cell       Date:  2014-01-23       Impact factor: 17.970

7.  Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling.

Authors:  Jed Long; Thomas P Garner; Maya J Pandya; C Jeremy Craven; Ping Chen; Barry Shaw; Michael P Williamson; Robert Layfield; Mark S Searle
Journal:  J Mol Biol       Date:  2009-11-17       Impact factor: 5.469

8.  TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.

Authors:  Manohar Pilli; John Arko-Mensah; Marisa Ponpuak; Esteban Roberts; Sharon Master; Michael A Mandell; Nicolas Dupont; Wojciech Ornatowski; Shanya Jiang; Steven B Bradfute; Jack-Ansgar Bruun; Tom Egil Hansen; Terje Johansen; Vojo Deretic
Journal:  Immunity       Date:  2012-08-24       Impact factor: 31.745

Review 9.  p62 in Cancer: Signaling Adaptor Beyond Autophagy.

Authors:  Jorge Moscat; Michael Karin; Maria T Diaz-Meco
Journal:  Cell       Date:  2016-10-20       Impact factor: 41.582

10.  Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy.

Authors:  Bettina Wurzer; Gabriele Zaffagnini; Dorotea Fracchiolla; Eleonora Turco; Christine Abert; Julia Romanov; Sascha Martens
Journal:  Elife       Date:  2015-09-28       Impact factor: 8.140
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  2 in total

1.  TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1.

Authors:  Katrine Stange Overå; Juncal Garcia-Garcia; Zambarlal Bhujabal; Ashish Jain; Aud Øvervatn; Kenneth Bowitz Larsen; Vojo Deretic; Terje Johansen; Trond Lamark; Eva Sjøttem
Journal:  J Cell Sci       Date:  2019-12-02       Impact factor: 5.285

Review 2.  History of the Selective Autophagy Research: How Did It Begin and Where Does It Stand Today?

Authors:  Vladimir Kirkin
Journal:  J Mol Biol       Date:  2019-05-11       Impact factor: 5.469
  2 in total

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