Nattaporn Tesavibul1, Sutasinee Boonsopon2, Pitipol Choopong2, Sujintana Tanterdtham2,3. 1. Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. Nattaporn.tes@mahidol.edu. 2. Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. 3. Department of Ophthalmology, Nakornpathom Hospital, 196 Tesa 7 Road, Prapathomchedi, Muang, Nakornpathom, 73000, Thailand.
Abstract
PURPOSE: To describe a proportion of uveitis and to analyse differences between immune-related uveitis and infectious uveitis groups. METHODS: A retrospective study of 458 uveitis patients were categorized into immune-related uveitis, infectious uveitis, masquerade, and undetermined groups. The pattern of inflammation was described. Subgroup analysis was performed to compare pattern differences between immune-related uveitis and infectious uveitis groups. RESULTS: The most common location of inflammation was the anterior eye segment. Vogt-Koyanagi-Harada disease was the most common identifiable cause. From multivariate analysis, variables found to be significantly different between immune-related uveitis group and infectious uveitis group were age of onset, presence of systemic autoimmune diseases, HIV infection, and laterality. CONCLUSIONS: Idiopathic anterior uveitis was the most prevalent diagnosis. Vogt-Koyanagi-Harada disease was the most common identifiable uveitis. Most immune-related uveitis patients were young and presented with chronic bilateral panuveitis, with most patients in the infectious uveitis group presenting with chronic unilateral posterior uveitis.
PURPOSE: To describe a proportion of uveitis and to analyse differences between immune-related uveitis and infectious uveitis groups. METHODS: A retrospective study of 458 uveitispatients were categorized into immune-related uveitis, infectious uveitis, masquerade, and undetermined groups. The pattern of inflammation was described. Subgroup analysis was performed to compare pattern differences between immune-related uveitis and infectious uveitis groups. RESULTS: The most common location of inflammation was the anterior eye segment. Vogt-Koyanagi-Harada disease was the most common identifiable cause. From multivariate analysis, variables found to be significantly different between immune-related uveitis group and infectious uveitis group were age of onset, presence of systemic autoimmune diseases, HIV infection, and laterality. CONCLUSIONS:Idiopathic anterior uveitis was the most prevalent diagnosis. Vogt-Koyanagi-Harada disease was the most common identifiable uveitis. Most immune-related uveitispatients were young and presented with chronic bilateral panuveitis, with most patients in the infectious uveitis group presenting with chronic unilateral posterior uveitis.
Authors: Nisha R Acharya; Vivien M Tham; Elizabeth Esterberg; Durga S Borkar; John V Parker; Aleli C Vinoya; Aileen Uchida Journal: JAMA Ophthalmol Date: 2013-11 Impact factor: 7.389